Xaira Therapeutics
Healthcare & Life SciencesDirect Greenhouse career site

AI in Residence

Pay
$10,000 – $15,000 per month
Location
South San Francisco, CA · On-site
Job type
Full-time
Level
Mid-level
Listed
31 days ago

Skills & highlights for this role

  • machine learning
  • generative AI models
  • foundation models

Also useful

  • Nature Methods
  • Cell Systems
  • open-source contributions

About the role

AI in Residence is a highly selective role at the intersection of frontier machine learning and drug discovery. Designed as an industry alternative to a traditional postdoctoral position, the program is for exceptional researchers and engineers who want to apply advanced AI to real biomedical problems end to end, from data to deployed systems.

Residents join a small cohort working on high-impact AI efforts across Xaira. You'll collaborate closely with AI scientists, research engineers, and drug discovery teams to design, build, and ship machine learning capabilities that directly influence therapeutic programs. This is hands-on, system-level work with real scientific consequence.

We're looking for candidates with technical depth, intellectual independence, strong research judgment, and evidence of delivering high-quality work-whether through publications, open-source, or production systems.

What You'll Do

  • Develop and advance ML models for biological, preclinical, and translational datasets (e.g., multimodal omics, imaging, text, assay data)
  • Design and implement scalable pipelines for data curation, training, evaluation, and inference integrated into discovery workflows
  • Own projects end-to-end: problem framing -> prototyping -> validation -> deployment
  • Evaluate robustness and reliability (generalization, uncertainty, failure modes), plus interpretability where it supports scientific decision-making
  • Contribute technical leadership by proposing new directions, shaping platform capabilities, and raising engineering/research standards through collaboration

Examples include (not limited to)

  • Foundation / representation models over multimodal biological and translational data
  • Methods for small, biased, noisy datasets; distribution shift; and uncertainty estimation
  • ML systems for experimental prioritization, assay interpretation, or translational signal discovery
  • Evaluation frameworks and benchmarks tailored to discovery decision-making
  • Tooling that makes models usable by scientists (interfaces, automation, monitoring)

What Success Looks Like

  • You ship one or more models or pipelines that are used in real discovery workflows
  • Your work improves decision quality (e.g., better prioritization, faster iteration, clearer uncertainty)
  • You raise the bar on evaluation rigor and reproducibility (strong baselines, error analysis, reliable metrics)
  • You leave behind maintainable systems (tests, documentation, monitoring) that others can build on

We Value

  • Strong research judgment: choosing the right problems and knowing what "good evidence" looks like
  • Rigor: careful experimental design, ablations, error analysis, and honest reporting
  • Systems thinking: reliability, scalability, and maintainability-not just prototypes

Clear communication: writing, documentation, and sharing decisions/assumptions:

  • Collaborative execution with scientific and engineering partners

Program Structure

  • Duration
  • 6-12 months
  • Start Dates

Currently accepting applications for Fall 2026 and Winter/Spring 2027 starts.

Cohort Size

Small, highly selective cohort to enable meaningful ownership and close collaboration

Mentorship & Support

Dedicated technical mentor, plus structured feedback from senior AI, engineering, and scientific leadership

Publications & Presentations

  • We value scientific contribution and may support publications and conference presentations when appropriate.
  • Publication scope and timing depend on project needs and are subject to internal review (e.g., IP and confidentiality).
  • Authorship follows standard contribution-based guidelines.

The Company consents to Employee completing, publishing, and maintaining the manuscript and repositories listed on Exhibit A, including bona fide revisions during peer review, provided such work is performed on Employee's own time and equipment, uses no Company resources or Proprietary Information, and does not relate to the Company's business or actual or anticipated research and development. This consent extends only to rights held by Employee and does not address or affect any rights of third parties.

We encourage applications from candidates who meet most of the following

  • Recent MS or PhD graduates (or equivalent research experience) in ML/AI, computational biology, biomedical engineering, or related fields
  • Evidence of research excellence through high-quality publications or artifacts. Top venues (e.g., NeurIPS, ICML, ICLR, CVPR, ACL; Nature Methods, Cell Systems) are a plus, but strong preprints, open-source contributions, or shipped systems with demonstrated impact are equally compelling
  • Demonstrated ability to lead substantial technical work with originality-new modeling ideas, rigorous experiments, or production-grade systems adopted by others
  • Motivation to translate rigorous research into reliable, deployable AI systems that support therapeutic discovery

Additional information

Please include a brief cover letter describing your interest in this role, why you're excited about this area, and what you hope to gain from the experience.

Compensation

The expected monthly compensation range is $10,000-$15,000, depending on experience and qualifications. We are open to higher compensation for candidates with exceptional experience or impact.

About Xaira Therapeutics

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification.

Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

Read the original posting

From Xaira Therapeutics's careers page, first listed on Rolev.ai on October 10, 2026. Rolev.ai is not the employer.

How Rolev.ai helps with this application

Rolev.ai is a job search and application tool for US job seekers. For this AI in Residence role at Xaira Therapeutics, it shows how your resume fits, tailors your resume to the posting, and prepares the application for you to review.

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Common questions

What is the salary for the AI in Residence role at Xaira Therapeutics?

The AI in Residence posting at Xaira Therapeutics states compensation of $10,000 – $15,000 per month. It is listed as a full-time position. Final pay may depend on location, experience, and interview evaluation on Xaira Therapeutics's official career site.

Where is the AI in Residence job at Xaira Therapeutics located?

This AI in Residence position at Xaira Therapeutics is located in South San Francisco, CA (On-site). Always check Xaira Therapeutics's application page for specific state eligibility or relocation policies.

What qualifications are required for AI in Residence at Xaira Therapeutics?

For the AI in Residence role, Xaira Therapeutics highlights experience with machine learning, generative AI models, foundation models. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.

How do I apply for the AI in Residence position at Xaira Therapeutics?

This listing links directly to Xaira Therapeutics's Greenhouse application page. You can apply directly on Xaira Therapeutics's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Greenhouse application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.