Associate Director, Statistical Programming
- Pay
- $172,000 – $258,000 per year
- Location
- Boston, MA · On-site
- Job type
- Full-time
- Level
- Director
- Experience
- 8+ years
- Education
- Bachelor's degree
- Listed
- 21 days ago
Skills & highlights for this role
- SAS programming
- CDISC SDTM and ADaM
- eCTD submissions
Also useful
- R
- Python
- CRO management
Summary
Tango has an exciting opportunity to join our growing Biostatistics team as an Associate Director, Statistical Programming, reporting to the Senior Director of Statistical Programming. In this role, you will be responsible for study-specific statistical programming activities, maintaining programming infrastructure, and ensuring compliance with SOPs to deliver high-quality, timely outputs.
Your Role
- Lead and manage the statistical programming activities for clinical trials and studies, ensuring high-quality and timely deliverables for CSR, publications, presentations, various reports for health authority submissions, clinical data review, and ad hoc analysis either internally or through CRO partners
- Develop, validate, and maintain analysis datasets (SDTM, ADaM), tables, listings, and figures, TLFs) in accordance with regulatory guidelines and internal standards
- Review key clinical study or program documents
- Perform complex statistical analyses and simulations using SAS to support clinical trial design and data interpretation; manage macro library and templates for efficiently preparing, processing, analyzing clinical data and validating analysis results
- Provide expertise in statistical programming for regulatory submissions (e.g., FDA, EMA), including electronic submission standards (eCTD)
- Participate in Tango's Data Governance Team to build and maintain secure statistical computing and programming infrastructure
- Collaborate with biostatisticians, data managers, and cross-functional team members to define programming strategies and requirements, establish project timelines, and perform statistical analyses
- Manage and provide oversight of CROs to ensure high-quality statistical analysis deliverables (datasets, TLFs, etc.) within timeline and budget
- Author or Review SDTM and ADaM specifications to ensure compliance to CDISC standards
- Develop SAS code, manage macro library and templates for efficiently preparing, processing, analyzing clinical data, and validating analysis results
- Author and/or review statistical analysis related SOPs
- Stay current with industry trends, best practices, and emerging technologies in statistical programming and data analysis
- Additional duties and responsibilities as required
What You Bring
- Bachelor's or Master's degree in statistics, life sciences, computer science, or related field with at least 8 years' statistical programming experience
- Solid understanding of industry standards applicable to clinical study data and regulatory reporting requirements including eCTD and CDISC implementation
- Expert level expertise in SAS programming (Base, Macro, STAT, GRAPH, SQL) is essential; with experience delivering complex programming assignments, macros, and analyses
- Experience with R and Python
- Extensive experience in early-phase clinical studies including programming and validation of SDTM and ADaM data sets, tables, listings and figures
- Experience managing CROs for outsourced statistical programming activities
- Expertise in the requirements and technology to support electronic submissions
- Experience in oncology preferred
- Experience with BLA or NDA/sNDA submissions to FDA/EMA required
- Strong analytical and communication skills
Pay and benefits
Salary range $172,000—$258,000 USD
Company Overview
Tango Therapeutics is a clinical-stage biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.
Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.
This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.
Tango's labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts.
Equal opportunity and legal notices
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
From Tango Therapeutics's careers page, first listed on Rolev.ai on October 19, 2026. Rolev.ai is not the employer.
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Common questions
What is the salary for the Associate Director, Statistical Programming role at Tango Therapeutics?
The Associate Director, Statistical Programming posting at Tango Therapeutics states compensation of $172,000 – $258,000 per year. It is listed as a full-time position. Final pay may depend on location, experience, and interview evaluation on Tango Therapeutics's official career site.
Where is the Associate Director, Statistical Programming job at Tango Therapeutics located?
This Associate Director, Statistical Programming position at Tango Therapeutics is located in Boston, MA (On-site). Always check Tango Therapeutics's application page for specific state eligibility or relocation policies.
What qualifications are required for Associate Director, Statistical Programming at Tango Therapeutics?
For the Associate Director, Statistical Programming role, Tango Therapeutics highlights 8+ years of relevant experience; a bachelor's degree; experience with SAS programming, CDISC SDTM and ADaM, eCTD submissions. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.
How do I apply for the Associate Director, Statistical Programming position at Tango Therapeutics?
This listing links directly to Tango Therapeutics's Greenhouse application page. You can apply directly on Tango Therapeutics's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Greenhouse application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.