Associate Director, Translational Medicine
- Pay
- $190,000 – $230,000 per year
- Location
- Waltham, MA
- Job type
- Full-time
- Level
- Director
- Experience
- 5+ years
- Education
- Doctorate
- Listed
- 31 days ago
Skills & highlights for this role
- biomarker assay validation
- IHC
- NGS
- flow cytometry
Also useful
- Spotfire
- R
- oncology trials
Stated benefits & perks
- Health
- Dental
- Vision
- 401k match
- Parental leave
The Role
The Associate Director, Translational Medicine plays a critical role in both Clinical Development and in support of nonclinical Research at Cogent. Reporting to Senior Director, Translational Medicine, you will play a critical role in representing the Translational Medicine function and provide subject matter expertise on cross-functional project teams
In partnership with Discovery Research and Clinical Development teams, you will lead the implementation of biomarker strategies to accelerate program transition from discovery research to clinical development. You will support decision making on patient selection/stratification, and utilizing biomarkers to predict drug efficacy and/or assess biological activity in humans and lead scientific and technical management implementation of clinical trial biomarker strategy.
Responsibilities
- Contribute to design of biomarker and/or diagnostic strategies for clinical programs
- Identify and utilize appropriate biomarkers to predict drug efficacy and/or assess biological activity in humans
- Oversee the use of biomarkers in clinical studies, writing protocols for incorporation of biomarkers in clinical trials, training trial sites or clinical CROs to ensure protocols are followed, and contribution to regulatory documents
- Analyze, interpret and report results of clinical biomarker analyses, including support of regulatory filings, congress presentations and publications.
- Direct the development, outsourcing and validation of clinically applicable biomarker assays
- Function as key point of contact with biomarker vendors
- In partnership with Research team, contribute to the identification of biomarkers, generation, and analysis of biomarker data to support assessment of target engagement, pathway modulation and disease modification to understand mechanism of action
- Collaborate with Research team for successful translation of nonclinical research to biomarkers suitable for implementation in clinical studies
Qualifications
- PhD in Biology, Pharmacology, Genetics/Genomics, or other related discipline with 5+ years of relevant biopharmaceutical industry experience.
- Strong understanding of clinical development and experience in clinical biomarker study execution including vendor management, data flow, interpretation and reporting. Experience with oncology trials is a plus.
- Current knowledge of FDA, EMA, ICH, GCP/GLP and other applicable guidelines related to qualification and validation of bioanalytical and biomarker assays
- Experience in broad range of platform technologies for biomarker assays (e.g., IHC, NGS, flow cytometry, PCR, and other technologies used in tumor tissue and liquid biopsies)
- Proficiency in data analysis software such as Spotfire or R
- Excellent interpersonal, leadership, communication, and time-management skills
- Desire to work within a fast-paced, innovative, and collaborative environment
Salary Range
$190,000 to $230,000 USD
Target Bonus: 20%
Exact compensation will vary based on skills, experience, and location.
Our Locations
Waltham, MA: Our headquarters is located in the Greater Boston life sciences community, with an open, collaborative office environment designed to support teamwork and connection. Employees benefit from convenient on-site amenities, including free on-site parking and gym facilities in the building.
Boulder, CO: Our Boulder location is home to Cogent's discovery research organization and a key scientific hub with strong leadership based on site. Situated in the greater Denver-Boulder biopharmaceutical corridor, this office plays a central role in advancing our discovery efforts and pipeline.
Our Offer To You
At Cogent Biosciences, we offer a competitive salary, bonus, and ongoing stock awards, alongside a benefits package that sets us apart. We cover 100% of medical, dental, and vision premiums for you and your family, and help reduce out-of-pocket costs by funding up to 75% of in-network deductibles.
Our benefits also include a 401(k) match with immediate vesting, generous paid time off, 12 weeks of fully paid parental leave, paid family and medical leave for all employees regardless of location, and company-paid short-term disability coverage for up to 20 weeks. Additional perks like wellness programs, tuition reimbursement, and inclusive family-forming support help you thrive at work and beyond.
Who We Are
Cogent Biosciences is a publicly traded biotechnology company focused on developing novel precision therapies to treat a broad range of patients with unmet medical needs. Cogent's lead program, bezuclastinib, is designed to selectively and potently inhibit exon 17 mutations found within the KIT receptor tyrosine kinase, including KIT D816V.
KIT D816V is responsible for driving a rare and serious condition called Systemic Mastocytosis, and exon 17 mutations are also found in patients with gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling.
Bezuclastinib has exhibited promising initial data across all three trials: APEX in AdvSM, SUMMIT in NonAdvSM and PEAK in GIST, including an encouraging safety profile across 600+ patients in single agent and combination dosing.
Equal opportunity and legal notices
We are proud to be an Equal Opportunity Employer. Our goal is to have a diverse workforce. We do not discriminate on the basis of race, age, color, religion, national origin, gender, sexual orientation, gender identity or expression, veteran status or disability, or any other status protected under federal, state, or local law. All employment is decided on the basis of qualifications, merit, and business need.
From Cogent Biosciences's careers page, first listed on Rolev.ai on October 10, 2026. Rolev.ai is not the employer.
How Rolev.ai helps with this application
Rolev.ai is a job search and application tool for US job seekers. For this Associate Director, Translational Medicine role at Cogent Biosciences, it shows how your resume fits, tailors your resume to the posting, and prepares the application for you to review.
See how you fit
Openings from employer career sites are ranked against your whole resume—and searchable inside Claude, ChatGPT, and Cursor via Rolev.ai MCP.
Tailor without inventing
Every change to your resume is checked against your original. New experience goes in only with your yes—zero fabricated claims.
Draft the full kit
Tailored and Full Match resumes, role-specific cover letters, and answers to employer screening questions are prepared in seconds.
1-Click Extension Autofill
The Chrome extension fills the employer's Greenhouse, Workday, Lever, or Ashby form in 1 click. You review it and press Submit.
Common questions
What is the salary for the Associate Director, Translational Medicine role at Cogent Biosciences?
The Associate Director, Translational Medicine posting at Cogent Biosciences states compensation of $190,000 – $230,000 per year. It is listed as a full-time position. Final pay may depend on location, experience, and interview evaluation on Cogent Biosciences's official career site.
Where is the Associate Director, Translational Medicine job at Cogent Biosciences located?
This Associate Director, Translational Medicine position at Cogent Biosciences is located in Waltham, MA. Always check Cogent Biosciences's application page for specific state eligibility or relocation policies.
What qualifications are required for Associate Director, Translational Medicine at Cogent Biosciences?
For the Associate Director, Translational Medicine role, Cogent Biosciences highlights 5+ years of relevant experience; a doctorate; experience with biomarker assay validation, IHC, NGS, flow cytometry. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.
How do I apply for the Associate Director, Translational Medicine position at Cogent Biosciences?
This listing links directly to Cogent Biosciences's Greenhouse application page. You can apply directly on Cogent Biosciences's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Greenhouse application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.