Associate Scientist, Pilot Lab, tLNP Drug Product
- Pay
- $95,000 – $120,000 per year
- Location
- Cambridge, MA · On-site
- Job type
- Full-time
- Level
- Entry level
- Experience
- 4+ years
- Listed
- 31 days ago
Skills & highlights for this role
- lipid nanoparticle formulation
- nucleic acid delivery
- dynamic light scattering
- RiboGreen assay
Also useful
- tangential flow filtration
- microfluidic mixing
- in vivo studies
Key Responsibilities
- Design, formulate, and characterize lipid nanoparticle (LNP) systems for nucleic acid delivery across preclinical manufacturing and technology development stages.
- Develop, optimize and operationalize formulation processes and scale-up approaches (e.g., TFF, ultrafiltration)
- Troubleshoot formulation and process challenges to enhance robustness, reproducibility, and scalability
- Generate high-quality, reproducible data and maintain thorough documentation in electronic lab notebooks
- Prepare LNP formulations to support internal research and partner programs
- Collaborate cross-functionally with analytical, translational and platform teams to advance pre-clincial manufacturing and pilot lab goals
- Present data and insights clearly to internal teams and contribute to scientific discussions and decision-making
Professional Experience & Qualifications
- 4+ years (M.Sc.) or 6+ years (B.Sc.) of relevant industry experience in LNP formulation optimizations and drug delivery with strong background in nucleic acid therapeutics and education in life sciences or engineering (Pharmaceutical Sciences, Biomedical Engineering, Biochemistry, etc)
- Level (Associate Scientist or Scientist I) will be determined based on experience, technical expertise, and demonstrated impact.
- Hands-on experience in nanoparticle or LNP formulation and characterization
- Strong understanding of drug delivery systems, particularly for nucleic acid therapeutics
- Experience with nanoparticle characterization techniques (e.g., DLS, zeta potential, fluorescence-based assays such as Ribogreen, chromatography)
- Demonstrated ability to design, execute, and troubleshoot experiments independently
- Strong data analysis, documentation, and communication skills
Preferred Qualifications
- Familiarity with formulation process technologies (e.g., microfluidic mixers, pumping systems, TFF)
- Experience supporting in vivo studies or translating formulations from research to preclinical scale
About Sail Biomedicines
Sail Biomedicines is seeking a scientist to advance our lipid nanoparticle (LNP) manufacturing platform for nucleic acid therapeutics. Sail Biomedicines is seeking a highly talented and self-motivated individual to develop and operationalize lipid nanoparticle formulations at pre-clinical and pilot lab scales. The successful candidate will contribute to preclinical pipeline programs, working at interface of manufacturing, formulation science, analytical characterization, and process development.
Equal opportunity and legal notices
Sail Biomedicines is an Equal Opportunity Employer. Sail does not discriminate based on race, religion, color, sex, gender identity, sexual orientation, age, national origin, veteran status, or any other status protected under federal, state, or local law.
From Sail Biomedicines's careers page, first listed on Rolev.ai on October 10, 2026. Rolev.ai is not the employer.
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Common questions
What is the salary for the Associate Scientist, Pilot Lab, tLNP Drug Product role at Sail Biomedicines?
The Associate Scientist, Pilot Lab, tLNP Drug Product posting at Sail Biomedicines states compensation of $95,000 – $120,000 per year. It is listed as a full-time position. Final pay may depend on location, experience, and interview evaluation on Sail Biomedicines's official career site.
Where is the Associate Scientist, Pilot Lab, tLNP Drug Product job at Sail Biomedicines located?
This Associate Scientist, Pilot Lab, tLNP Drug Product position at Sail Biomedicines is located in Cambridge, MA (On-site). Always check Sail Biomedicines's application page for specific state eligibility or relocation policies.
What qualifications are required for Associate Scientist, Pilot Lab, tLNP Drug Product at Sail Biomedicines?
For the Associate Scientist, Pilot Lab, tLNP Drug Product role, Sail Biomedicines highlights 4+ years of relevant experience; experience with lipid nanoparticle formulation, nucleic acid delivery, dynamic light scattering, RiboGreen assay. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.
How do I apply for the Associate Scientist, Pilot Lab, tLNP Drug Product position at Sail Biomedicines?
This listing links directly to Sail Biomedicines's Greenhouse application page. You can apply directly on Sail Biomedicines's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Greenhouse application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.