Personalis
Healthcare & Life SciencesDirect Greenhouse career site

Histotechnician, 2nd Shift (Mon - Fri)

Pay
$40 – $50 per hour
Location
Fremont, CA · On-site
Job type
Full-time
Level
Mid-level
Experience
3+ years
Education
Associate degree
Listed
31 days ago

Skills & highlights for this role

  • HT certification (ASCP)
  • microtomy
  • H&E staining
  • tissue embedding
  • LIMS documentation

Also useful

  • IHC
  • digital slide imaging
  • pathology report interpretation

Stated benefits & perks

  • Medical
  • Dental
  • Vision
  • 401k match
  • Tuition

Summary

Under the direction of the department supervisor, technical/clinical consultant, and laboratory director, the Histotechnician will be responsible for processing FFPE specimens for microscopic evaluation to support our molecular diagnostics test offerings.

Available Shift

  • Monday - Friday, 2:00pm - 10:30pm

Responsibilities

  • Perform sectioning of tissue using a microtome and mounting on glass slides
  • Perform routine staining of tissue sections with automated and/or manual staining techniques
  • Perform automated and/or manual coverslipping of slides
  • Generate digital slide images for pathologist examination
  • Perform manual and automated macrodissection
  • Operate and perform instrument maintenance
  • Perform histology lab functions while following laboratory safety and quality policies
  • Comply with standard laboratory operating policies and procedures
  • Use of good documentation practices to record specimen data manually or in Laboratory Information Management Systems
  • Help meet TAT goals while maintaining high-quality productivity
  • Maintain clean and organized work areas within the laboratory
  • Report problems to the department supervisor/manager to ensure timely resolution

Requirements

  • Associate's degree in chemical/physical/biological science or completion of a NAACLS-accredited Histotechnology program; Bachelor's degree in a laboratory science curriculum preferred
  • Minimum of 3+ years experience working in a high-volume histology laboratory performing microtomy of various tissue types, H&E staining, and tissue embedding
  • HT or HTL certification from ASCP
  • Experience working in IHC and digital imaging, tissue/tumor identification, and proficiency in reading pathology reports, a plus
  • Excellent attention to detail, organization, and time management skills
  • Ability to communicate effectively with excellent interpersonal skills
  • Physical demands include stooping, turning, bending, squatting, kneeling, and the ability to lift up to 25 lbs.

Pay and benefits

The hiring range for this position is $40.00 to $50.00 per hour, which may factor in various geographic regions. This shift is eligible for a shift differential pay bonus. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors.

Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)

#LI-JT1 #LI-Onsite

About Personalis

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time.

Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Read the original posting

From Personalis's careers page, first listed on Rolev.ai on October 10, 2026. Rolev.ai is not the employer.

How Rolev.ai helps with this application

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Common questions

What is the salary for the Histotechnician, 2nd Shift (Mon - Fri) role at Personalis?

The Histotechnician, 2nd Shift (Mon - Fri) posting at Personalis states compensation of $40 – $50 per hour. It is listed as a full-time position. Final pay may depend on location, experience, and interview evaluation on Personalis's official career site.

Where is the Histotechnician, 2nd Shift (Mon - Fri) job at Personalis located?

This Histotechnician, 2nd Shift (Mon - Fri) position at Personalis is located in Fremont, CA (On-site). Always check Personalis's application page for specific state eligibility or relocation policies.

What qualifications are required for Histotechnician, 2nd Shift (Mon - Fri) at Personalis?

For the Histotechnician, 2nd Shift (Mon - Fri) role, Personalis highlights 3+ years of relevant experience; a associate degree; experience with microtomy, H&E staining, tissue embedding, LIMS documentation. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.

How do I apply for the Histotechnician, 2nd Shift (Mon - Fri) position at Personalis?

This listing links directly to Personalis's Greenhouse application page. You can apply directly on Personalis's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Greenhouse application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.