Vrtx
Healthcare & Life SciencesDirect Workday career site

Innovation & Business Transformation, Sr. Manager

Pay
$134,200 – $201,200 per year
Location
Boston, MA · Hybrid
Job type
Full-time
Level
Director
Experience
6+ years
Education
Bachelor's degree
Listed
23 days ago

Skills & highlights for this role

  • business process mapping
  • requirements gathering
  • project management

Stated benefits & perks

  • Health
  • Dental
  • Vision
  • 401k match

General Summary

The Senior Manager, Innovation and Business Transformation drives the execution of defined technology-enabled transformation initiatives across Medical Writing Science (MWS). The role assesses business needs and workflows, translates requirements into practical implementation plans, coordinates testing and implementation activities, and enables successful adoption and continuous improvement of new capabilities.

Working closely with MWS leaders, users, and enterprise technology partners, the Senior Manager ensures solutions address established business needs, are effectively implemented, and improve scientific and operational ways of working. Key Duties and

Pay and benefits

Execute defined technology-enabled transformation initiatives, coordinating activities, milestones, stakeholders, and deliverables to achieve established business outcomes. Assess current-state workflows, identify pain points and user needs, and contribute to future-state process design and improvement recommendations.

Translate business needs into detailed requirements, process maps, user stories, acceptance criteria, workflow specifications, implementation plans, and success measures. Partner with MWS subject matter experts, users, and enterprise technology teams to validate workflows and requirements and support delivery of fit-for-purpose solutions.

Evaluate proposed capabilities against defined business requirements, workflow fit, usability, quality, risk, and expected outcomes, providing recommendations to initiative leaders. Plan and facilitate prototypes, pilots, workflow validation, user acceptance testing, and implementation activities, documenting outcomes and coordinating resolution of identified issues.

Execute organizational readiness and change activities for assigned initiatives, including impact assessment, stakeholder engagement, communications, training, user support, and adoption. Monitor adoption, user feedback, process performance, and initiative outcomes using appropriate reporting and enablement tools; identify improvement opportunities and support optimization and sustained use.

Coordinate project stakeholders and activities, manage delivery risks and dependencies within assigned work, and escalate significant decisions, risks, and trade-offs to initiative leadership. Knowledge and Skills: Experience supporting business transformation, digital innovation, AI enablement, process improvement, automation, analytics, or technology-enabled workflow initiatives.

Demonstrated ability to translate business and user needs into requirements, process maps, user stories, acceptance criteria, implementation plans, and success measures. Ability to analyze current-state workflows, identify pain points, and contribute to practical future-state process improvements.

Working knowledge of AI-enabled capabilities, digital platforms, automation, analytics, and emerging technologies and their potential application to scientific and operational workflows. Experience supporting or facilitating prototypes, pilots, user acceptance testing, workflow validation, implementation, and post-implementation improvement.

Experience supporting change and adoption activities, including stakeholder engagement, communications, training, user feedback, and adoption monitoring. Strong analytical, project management, facilitation, and problem-solving skills, with the ability to manage activities, dependencies, risks, and competing priorities.

Strong communication and collaboration skills, with the ability to work effectively across scientific, business, user, technology, and governance stakeholders. Education and Experience: 6 years of experience working in the biotechnology or pharmaceutical industry, or in a relevant technology, engineering business field, or the equivalent combination of education and experience.

Bachelor's degree in technology discipline or equivalent At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends.

We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range: $134,200 - $201,200 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements.

Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.

From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at

Read the original posting

From Vrtx's careers page, first listed on Rolev.ai on October 18, 2026. Rolev.ai is not the employer.

How Rolev.ai helps with this application

Rolev.ai is a job search and application tool for US job seekers. For this Innovation & Business Transformation, Sr. Manager role at Vrtx, it shows how your resume fits, tailors your resume to the posting, and prepares the application for you to review.

  • See how you fit

    Openings from employer career sites are ranked against your whole resume—and searchable inside Claude, ChatGPT, and Cursor via Rolev.ai MCP.

  • Tailor without inventing

    Every change to your resume is checked against your original. New experience goes in only with your yes—zero fabricated claims.

  • Draft the full kit

    Tailored and Full Match resumes, role-specific cover letters, and answers to employer screening questions are prepared in seconds.

  • 1-Click Extension Autofill

    The Chrome extension fills the employer's Greenhouse, Workday, Lever, or Ashby form in 1 click. You review it and press Submit.

Common questions

What is the salary for the Innovation & Business Transformation, Sr. Manager role at Vrtx?

The Innovation & Business Transformation, Sr. Manager posting at Vrtx states compensation of $134,200 – $201,200 per year. It is listed as a full-time position. Final pay may depend on location, experience, and interview evaluation on Vrtx's official career site.

Where is the Innovation & Business Transformation, Sr. Manager job at Vrtx located?

This Innovation & Business Transformation, Sr. Manager position at Vrtx is located in Boston, MA (Hybrid). Always check Vrtx's application page for specific state eligibility or relocation policies.

What qualifications are required for Innovation & Business Transformation, Sr. Manager at Vrtx?

For the Innovation & Business Transformation, Sr. Manager role, Vrtx highlights 6+ years of relevant experience; a bachelor's degree; experience with business process mapping, requirements gathering, project management. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.

How do I apply for the Innovation & Business Transformation, Sr. Manager position at Vrtx?

This listing links directly to Vrtx's Workday application page. You can apply directly on Vrtx's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Workday application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.