Portfolio & Program Management Platform Business Owner, Director
- Location
- Boston, MA
- Listed
- 3 days ago
About the role
The Portfolio & Program Management Platform Business Owner, Director, is an individual contributor leadership role within the Portfolio & Program Management (PPM) organization and newly formed Center of Excellence, serving as the business owner for platforms and AI-enabled capabilities that support PPM and the broader Transactions, Alliances, and Portfolio Management (TAPM) organization.
The incumbent owns the business strategy, governance, requirements, adoption, and value realization for PPM/TAPM technology platforms and AI-enabled capabilities, in partnership with IT and other enabling functions responsible for technical delivery, architecture, security, and support.
This role leads cross-functional business efforts to evolve project and portfolio management capabilities, strengthen data governance, and advance an integrated, AI-ready planning and reporting environment.
Key Duties and Responsibilities
- Partner with TAPM leadership and IT to shape and execute the business roadmap for PPM/TAPM technology platforms and AI-enabled capabilities, driving delivery of capabilities that enhance portfolio planning, decision-making, and operational effectiveness
- Serve as business owner for the PPM project management platform(s), including MS Project Server Subscription Edition as the business system of record for functional and integrated project plans
- Lead business ownership of AI tools and use cases across PPM and TAPM to improve reporting, analytics, automation, and process efficiency
- Ensure project and portfolio management data effectively supports portfolio reporting, resource planning, financial planning, and enterprise decision-making
- Lead cross-functional business efforts to define requirements, evaluate options, prioritize needs, and support selection of future-state project management and portfolio technology solutions in partnership with IT and other delivery partners
- Coordinate integration across project plans, portfolio data, resources, and financials to support a more connected planning environment and improved data quality
- Define and maintain business processes for platform governance, data governance, user support, issue triage, adoption, and continuous improvement, while partnering with IT for technical administration and support
- Partner with TAPM leaders and cross-functional stakeholders to align priorities, influence decisions, and support adoption of systems, tools, and process changes
- Oversee business ownership and effective use of other department technologies, including collaboration tools such as SharePoint, as applicable, with technical administration supported by appropriate enabling functions
Knowledge and Skills
- Broad understanding of project and portfolio management systems, including direct experience with MS Project; familiarity with other industry-relevant platforms preferred
- Understanding of how project planning data supports portfolio reporting, resource planning, financial planning, and portfolio decision-making
- Experience serving as a business owner or business product owner for enterprise platforms, including governance, requirements definition, adoption, user support, issue triage, and partnership with IT delivery teams
- Knowledge of AI and automation applications in business processes; experience with Power BI or similar reporting and visualization tools preferred
- Knowledge of data governance, data quality, and stewardship practices
- Pharmaceutical drug discovery and development expertise across multiple disciplines
- Strong collaboration, communication, organizational, and problem-solving skills, with the ability to influence stakeholders across a matrixed organization
Education and Experience
- Typically requires a bachelor's degree in Business, Life Sciences, Program/Portfolio Management, Information Systems, Data Science, or a related field
- Typically requires 12 years of experience, or the equivalent combination of education and experience
- Relevant experience in the pharmaceutical, biotechnology, or related industry supporting portfolio management, program management, business systems, or operations is required
- Experience leading cross-functional initiatives and working with senior stakeholders is required
- Supervisory or people leadership experience is preferred but not required
Additional information
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range
$192,000 - $288,000
Disclosure Statement
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation: Hybrid-Eligible Or On-Site Eligible
In this Hybrid-Eligible role, you can choose to be designated as
- Hybrid: work remotely up to two days per week; or select
- On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at
Equal opportunity and legal notices
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
From Vrtx's careers page, first listed on Rolev.ai on November 6, 2026. Rolev.ai is not the employer.
How Rolev.ai helps with this application
Rolev.ai is a job search and application tool for US job seekers. For this Portfolio & Program Management Platform Business Owner, Director role at Vrtx, it shows how your resume fits, tailors your resume to the posting, and prepares the application for you to review.
See how you fit
Openings from employer career sites are ranked against your whole resume—and searchable inside Claude, ChatGPT, and Cursor via Rolev.ai MCP.
Tailor without inventing
Every change to your resume is checked against your original. New experience goes in only with your yes—zero fabricated claims.
Draft the full kit
Tailored and Full Match resumes, role-specific cover letters, and answers to employer screening questions are prepared in seconds.
1-Click Extension Autofill
The Chrome extension fills the employer's Greenhouse, Workday, Lever, or Ashby form in 1 click. You review it and press Submit.
Common questions
Where is the Portfolio & Program Management Platform Business Owner, Director job at Vrtx located?
This Portfolio & Program Management Platform Business Owner, Director position at Vrtx is located in Boston, MA. Always check Vrtx's application page for specific state eligibility or relocation policies.
How do I apply for the Portfolio & Program Management Platform Business Owner, Director position at Vrtx?
This listing links directly to Vrtx's Workday application page. You can apply directly on Vrtx's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Workday application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.