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Job Details

A computational biologist position is immediately available in the laboratory of Dr. Fadia Ibrahim in the Department of Biochemistry and Molecular Biology, at Thomas Jefferson University. Our research program is focused on studying the molecular mechanism of a novel co-translational RNA decay process "ribothrypsis" and investigating the role of RNA dysregulation in neurodegenerative diseases.

Our research integrates molecular biology, biochemistry, innovative RNA sequencing technologies, and advanced computational approaches. We are seeking a highly motivated computational biologist to support ongoing research projects, develop and implement bioinformatics tools and pipelines, and oversee the processing, management, and analysis of next generation sequencing (NGS) data.

Required Qualifications

• Ph.D. in Computational Biology, Bioinformatics, Computational Sciences, or a related discipline.
• Proficiency in R and Python and in working in Linux/Unix environments with commandline-based bioinformatics tools.
• Experience analyzing and interpreting NGS data, including RNA-Seq and Ribo-Seq, with expertise in data evaluation and visualization (e.g., differential expression, ribosome occupancy, poly(A) tail analysis, and modifications detection).
• Basic knowledge of molecular biology techniques and familiarity with biological data.
• Knowledge of statistical methods and their applications to biological datasets.
• Strong analytical, problem-solving, and quantitative skills, with the ability to collaborate effectively in a multidisciplinary team environment.
• Publication track-record in relevant fields.

Preferred Qualifications

• Familiarity with NGS platforms, including Illumina and Oxford Nanopore Technologies.
• Demonstrated ability to integrate, mine, and analyze diverse large-scale biological datasets.
• Experience with commonly used bioinformatics resources, tools, and databases, including ENCODE, UCSC Genome Browser, Ensembl, Bioconductor, and NCBI databases.
• Experience managing computational servers and data storage and backup.
• Ability to formulate and develop scientific hypotheses that support ongoing research.
• Strong organizational, written, and verbal communication skills.

Additional information

Interested applicants are invited to submit a single PDF containing their CV, a cover letter outlining their research experience and interests, and the contact details of three referees.

• Work Shift
• Workday Day (United States of America)
• Worker Sub Type
• Regular
• Employee Entity
• Thomas Jefferson University
• Primary Location Address

1020 Locust Street, Philadelphia, Pennsylvania, United States of America

Nationally ranked, Jefferson, which is principally located in the greater Philadelphia region, Lehigh Valley and Northeastern Pennsylvania and southern New Jersey, is reimagining health care and higher education to create unparalleled value.

Jefferson is more than 65,000 people strong, dedicated to providing the highest-quality, compassionate clinical care for patients; making our communities healthier and stronger; preparing tomorrow's professional leaders for 21st-century careers; and creating new knowledge through basic/programmatic, clinical and applied research.

Thomas Jefferson University, home of Sidney Kimmel Medical College, Jefferson College of Nursing, and the Kanbar College of Design, Engineering and Commerce, dates back to 1824 and today comprises 10 colleges and three schools offering 200+ undergraduate and graduate programs to more than 8,300 students.

Jefferson Health, nationally ranked as one of the top 15 not-for-profit health care systems in the country and the largest provider in the Philadelphia and Lehigh Valley areas, serves patients through millions of encounters each year at 32 hospitals campuses and more than 700 outpatient and urgent care locations throughout the region.

Jefferson Health Plans is a not-for-profit managed health care organization providing a broad range of health coverage options in Pennsylvania and New Jersey for more than 35 years.

Benefits

Jefferson offers a comprehensive package of benefits for full-time and part-time colleagues, including medical (including prescription), supplemental insurance, dental, vision, life and AD&D insurance, short- and long-term disability, flexible spending accounts, retirement plans, tuition assistance, as well as voluntary benefits, which provide colleagues with access to group rates on insurance and discounts.

Colleagues have access to tuition discounts at Thomas Jefferson University after one year of full time service or two years of part time service. All colleagues, including those who work less than part-time (including per diem colleagues, adjunct faculty, and Jeff Temps), have access to medical (including prescription) insurance.

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