Postdoctoral Researcher - Biophysics

Summary

The Vasquez-Vivar Lab in the Department of Biophysics at the Medical College of Wisconsin is seeking a highly motivated Postdoctoral Fellow to join our research team focused on fetal brain injury and the mechanisms of acquired motor disorders in children.

We use a multidisciplinary approach that integrates redox biology, biochemical, and preclinical models to explore gain- and loss-of-function relationships and identify opportunities for therapeutic perinatal interventions.

This position offers an exciting opportunity for candidates passionate about redox cell biology, with the potential to develop novel experimental approaches and lead research projects in a collaborative and well-resourced environment.

The Department of Biophysics at the Medical College of Wisconsin has a rich tradition of innovation and excellence in redox and structural biology and biomedical imaging, with strengths in EPR (electron paramagnetic resonance), NMR (nuclear magnetic resonance), and MRI (clinical magnetic resonance imaging). MCW is Wisconsin's largest private research institution and the third-largest private medical school in the U.S. The institution fosters a collaborative environment that integrates basic science, clinical research, and education to advance biomedical knowledge and human health.

Primary Responsibilities

• Perform in vitro transcription, qPCR, and protein sequencing analysis.
• Complete expression, purification, and characterization of mammalian recombinant enzymes.
• Conduct biochemical assays to study loss or gain of function in cells expressing mutant proteins.
• Isolate cells from tissues, perform cell culture, and conduct microscopy/immunofluorescence assays.
• Analyze experimental data, interpret results, and contribute to manuscript preparation.
• Present research findings at lab meetings, institutional seminars, and scientific conferences
• Mentor and contribute to training and scientific development within the lab.
• Assist with the development of grant proposals and collaborative research initiatives.
• Other duties as assigned.

Knowledge - Skills - Abilities

• Required knowledge in biology, chemistry, mathematics, and statistics
• Documentation, records management and data utilization skills
• Complex problem solving, critical thinking, and resource management
• Excellent written and verbal communication skills

Qualifications

• Minimum Required Education: Ph.D. or PhD candidate within 3 months of the start date
• Minimum Required Experience: 0 years

Preferred Education

PhD in Neuroscience, Biochemistry, Cell Biology, Molecular Biology, or a related discipline.

Preferred Experience

• Hands-on experience in protein analysis, stem cell culture, and microscopy methods.
• Familiarity with enzyme-substrate docking analysis.
• Strong background in protein or redox signaling biochemistry.
• Proven ability to work independently, manage time effectively, and troubleshoot experiments.
• First-author publication record in peer-reviewed journals

Interested applicants should submit the following materials

• Cover letter outlining research interests and career goals
• Curriculum vitae (CV)
• Contact information for three professional references

Physical Requirements

Work requires occasionally lifting moderate weight materials, standing, or walking continuously.

Work Environment

Occasional exposure to dust, noise, temperature changes, or contact with water or other liquids. Work is performed in an environmentally controlled environment.

Sensory Acuity

Ability to detect and translate speech or other communication required. May occasionally require the ability to distinguish colors and perceive relative distances between objects.