Principal Data Scientist - DDSAI GD

About the role

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

• Job Function: Data Analytics & Computational Sciences
• Job Sub Function: Data Science
• Job Category: Scientific/Technology

All Job Posting Locations: Titusville, New Jersey, United States of America

Job Summary

J&J Innovative Medicine – Data, Data Science, and AI - Global Development (DDSAI GD) is seeking a Principal Data Scientist to lead end-to-end delivery of integrated analytical solutions for defined clinical-development and trial-operations business problems. This role owns solution definition, delivery, adoption, and use-case outcomes across connected stakeholder groups using ML, GenAI, optimization, and RWD.

Key Responsibilities

• Own the end-to-end definition, development, validation, deployment, and adoption of integrated data-science solutions for defined business problems.
• Lead predictive modeling, simulations, optimization, and GenAI applications for study feasibility, enrollment forecasting, country and site selection, protocol design, and operational planning.
• Apply clinical, operational, cost, and RWD—including EHR, claims, registries, and clinical-trial data—to generate evidence on patient populations, treatment pathways, feasibility, and operational risks.
• Lead RWD analytics that inform protocol feasibility, eligibility criteria, recruitment and retention, study design, comparative evidence, and external-control use cases.
• Develop LLM-enabled workflows for information extraction, protocol comparison, data harmonization, clinical-concept interpretation, and targeted workflow automation.
• Partner with clinical, operational, technology, and data stakeholders to frame questions, manage trade-offs, and translate outputs into adopted recommendations and measurable use-case outcomes.
• Apply model-validation, MLOps, documentation, privacy, data-quality, and responsible-AI standards; contribute reusable code, data assets, and technical patterns.
• Communicate methods, model outputs, assumptions, limitations, and decisions clearly to technical and nontechnical audiences.
• Mentor junior colleagues and strengthen delivery practices across project teams.

Required Qualifications

• Master’s degree in computer science, engineering, biostatistics, health economics, biomedical informatics, applied mathematics, or another quantitative discipline; PhD preferred.
• At least 5 years of industry experience leading end-to-end delivery of data-science solutions using ML, predictive modeling, optimization, NLP, GenAI, or RWD analytics.
• Demonstrated experience defining, validating, deploying, and driving adoption of analytical solutions that inform clinical-development, clinical-operations, or real-world evidence decisions.
• Hands-on experience with structured and unstructured clinical, operational, or RWD data, including multimodal modeling and time-series or simulation methods.
• Proficiency in Python and SQL, modern ML, optimization, and LLM-development libraries, and reproducible MLOps practices.
• Strong communication, stakeholder-management, and technical-leadership skills.

Preferred Qualifications

• Experience in healthcare, pharmaceutical development, MedTech, clinical development, or clinical operations.
• Experience applying RWD methods to clinical-trial design, including target-trial emulation, propensity methods, survival analysis, or time-to-event analysis.
• Experience delivering analytical products or applications used by clinical or business teams.

Additional information

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us, internal employees contact AskGS to be directed to your accommodation resource.

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Preferred Skills

Advanced Analytics, Coaching, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Digital Fluency, Econometric Models, Organizing, Process Improvements, Strategic Thinking, Technical Credibility, Workflow Analysis

The anticipated base pay range for this position is

$117,000.00 - $201,250.00

Additional Description for Pay Transparency

Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).

Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits:

Vacation –120 hours per calendar year

Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year

Holiday pay, including Floating Holidays –13 days per calendar year

Work, Personal and Family Time - up to 40 hours per calendar year

Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child

Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year

• Caregiver Leave – 80 hours in a 52-week rolling period10 days
• Volunteer Leave – 32 hours per calendar year
• Military Spouse Time-Off – 80 hours per calendar year