Principal Scientist, Lab Head, Immunology, Cell Therapy
- Pay
- $143,200 – $265,900 per year
- Location
- South San Francisco, CA · On-site
- Job type
- Full-time
- Level
- Director
- Experience
- 5+ years
- Education
- Doctorate
- Listed
- 21 days ago
Skills & highlights for this role
- cellular immunology
- T cell biology
- B cell biology
- mouse models
- preclinical development
Also useful
- humanized mouse models
- immune cell engineering
Stated benefits & perks
- Bonus eligible
The Opportunity
The Department of Immunology Discovery at Genentech is excited to announce an opportunity for a Principal Scientist, Lab Head, to lead a research group focused on designing next-generation cell therapies to treat autoimmune diseases.
The successful candidate will lead a highly productive research team, integrating efforts across cross-functional teams to identify new targets and therapeutic hypotheses, and to advance transformative therapeutics from preclinical studies into early clinical development.
The ideal candidate will have a deep understanding of cellular immunology principles and pathways relevant to the biology of autoimmune disease, including but not limited to inflammatory bowel disease, multiple sclerosis, lupus and chronic obstructive pulmonary disease.
Excellent communication skills are essential to facilitate fruitful collaborations with colleagues across a diverse array of departments, including computational biology, proteomics and tissue genomics, drug development, early clinical development, and translational medicine.
Key responsibilities include leading and managing a highly-productive research team, generating high-quality, original research that advances our understanding of autoimmune disease and contributing directly to the initiation and advancement of novel pipeline projects. The successful candidate may also play a critical role within cross-functional teams evaluating external business development opportunities to accelerate our cell therapy pipeline.
The ideal candidate will have
- PhD and postdoctoral training in Immunology, Cell Biology or related field
- A minimum of 5 years post-PhD experience with a record of high-impact publications (preprints considered), patents, and/or a proven track record advancing therapeutic candidates from pipeline entry to early clinical development
- Demonstrated expertise in cellular immunology and a deep understanding of pathways and immune cell types that contribute to autoimmune disease
- Outstanding leadership and a collaborative spirit, with a proven track record of working with multidisciplinary teams
- Excellent written and verbal communication skills, with the ability to communicate complex scientific concepts to multidisciplinary audiences
- Exceptional critical thinking skills, a commitment to rigorous experimental design and creative problem-solving, and a demonstrated ability to use data-driven insights to guide scientific decisions
Preferred qualifications
- Expertise in both B cell and T cell biology
- Experience engineering, modifying, and functionally evaluating human immune cells
- Experience working with mouse models, including humanized models
Relocation benefits are available for this job posting.
Pay and benefits
The expected salary range for this position based on the primary location of California is $143,200 to $265,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Equal opportunity and legal notices
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
From Roche's careers page, first listed on Rolev.ai on October 20, 2026. Rolev.ai is not the employer.
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Common questions
What is the salary for the Principal Scientist, Lab Head, Immunology, Cell Therapy role at Roche?
The Principal Scientist, Lab Head, Immunology, Cell Therapy posting at Roche states compensation of $143,200 – $265,900 per year. It is listed as a full-time position. Final pay may depend on location, experience, and interview evaluation on Roche's official career site.
Where is the Principal Scientist, Lab Head, Immunology, Cell Therapy job at Roche located?
This Principal Scientist, Lab Head, Immunology, Cell Therapy position at Roche is located in South San Francisco, CA (On-site). Always check Roche's application page for specific state eligibility or relocation policies.
What qualifications are required for Principal Scientist, Lab Head, Immunology, Cell Therapy at Roche?
For the Principal Scientist, Lab Head, Immunology, Cell Therapy role, Roche highlights 5+ years of relevant experience; a doctorate; experience with cellular immunology, T cell biology, B cell biology, mouse models, preclinical development. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.
How do I apply for the Principal Scientist, Lab Head, Immunology, Cell Therapy position at Roche?
This listing links directly to Roche's Workday application page. You can apply directly on Roche's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Workday application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.