Syneos Health
Direct Workday career site

Principal Site Activation Manager

Pay
$97,300 – $170,300 per year
Location
USA-NC-Morrisville-Hybrid
Listed
18 days ago

About the role

Principal Site Activation Manager Syneos Health® is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.

Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape. Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you'll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals.

We are agile and driven to deliver - for one another, our customers,, most importantly, for those in need.

Discover what your 25,000 future colleagues already know: Why Syneos Health * We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program. * We are committed to building an inclusive culture - where you can authentically be yourself.

Central to this is our purpose - Driven to Deliver - which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone's life. * We are continuously building the company we all want to work for and our customers want to work with. Why?

Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress.

Pay and benefits

Typical Responsibilities Lead and oversee global site activation activities from study start-up through site readiness. Develop and execute country and site activation strategies. Manage timelines, risks, and deliverables across multiple studies or programs. Partner closely with Clinical Operations, Regulatory Affairs, Contracts & Budgets, and external stakeholders.

Drive performance metrics and ensure activation milestones are achieved. Provide guidance and oversight to Site Activation Managers and study teams. Support issue escalation and resolution for complex start-up challenges. Ensure compliance with regulatory requirements, SOPs, and sponsor expectations. At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance.

We reward and recognize our people by providing valuable benefits and a quality-of-life balance.

The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time.

Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements. Salary Range: $97,300.00 - $170,300.00 The base salary range represents the anticipated low and high of the Syneos Health range for this position.

Actual salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role. Get to know Syneos Health Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you'll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health. Additional Information Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities.

Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract.

Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees.

Read the original posting

From Syneos Health's careers page, first listed on Rolev.ai on October 23, 2026. Rolev.ai is not the employer.

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Common questions

What is the salary for the Principal Site Activation Manager role at Syneos Health?

The Principal Site Activation Manager posting at Syneos Health states compensation of $97,300 – $170,300 per year. Final pay may depend on location, experience, and interview evaluation on Syneos Health's official career site.

Where is the Principal Site Activation Manager job at Syneos Health located?

This Principal Site Activation Manager position at Syneos Health is located in USA-NC-Morrisville-Hybrid. Always check Syneos Health's application page for specific state eligibility or relocation policies.

How do I apply for the Principal Site Activation Manager position at Syneos Health?

This listing links directly to Syneos Health's Workday application page. You can apply directly on Syneos Health's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Workday application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.