Research Fellow

About the role

Site: The Brigham and Women's Hospital, Inc.

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

The Koo Laboratory in the Division of Infectious Diseases at Brigham and Women's Hospital, Harvard Medical School, is seeking highly motivated post-doctoral Research Fellow candidates. In the Koo laboratory, we are dedicated to the development and application of novel diagnostic approaches for infections in immunocompromised hosts and the delineation of the epidemiology and pathophysiology of opportunistic pathogens, especially fungi, in these patient populations.

The candidate will be expected to have experience, or a high capacity to learn, murine pneumonia models, and molecular genetic techniques including spatial transcriptomic studies, and microbiologic/mycologic laboratory techniques. The team will include the Principal Investigator and other collaborating faculty, research scientists, postdoctoral fellows, and research assistants. We are seeking a Research Fellow with the enthusiasm to develop projects that will contribute to diverse and highly collaborative research programs.

The new hire will be appointed as a Research Fellow at the Massachusetts General Brigham and at the Harvard Medical School.

Qualifications

Important - Application Instructions

• This is a courtesy posting. Please do not submit your application through the Workday "Apply" button.
• Applications submitted only through Workday will not be forwarded to the hiring manager and may not be reviewed.

Principal Duties and Responsibilities

• Design, execute, and interpret research experiments
• Learn any number of molecular genomics techniques including single-cell RNAseq (scRNAseq), spatial transcriptomics, and other methods
• Maintain murine models and process murine tissues for more detailed evaluation
• U se advanced analytical chemistry techniques to define the breath volatile metabolite profile of patients with various bacterial, viral, and fungal pneumonias.
• Analyze mass spectroscopic and differential mobility spectroscopic data from laboratory experiments.
• Maintain a detailed record of experiments in a laboratory notebook
• Independently follow detailed protocols while working closely with a wide range of lab members (i.e., graduate students, postdocs, research assistants, staff scientists)
• Assist in training new Research assistants and Postdoctoral Fellows
• Responsible for troubleshooting problems and instructing others in highly specialized techniques.
• Investigate, create, and develop new methods and technologies for research advancements.
• Preparation of written data reports, including methodology, figure preparations, written description of the study in the form of manuscripts and/or progress reports.
• Contribute to research presentations at local, national, and international meetings.
• Oversight of laboratory research assistants and students participating on the projects, including training them, and assisting them with experimental design and implementation.
• Organize and/or draft material for the preparation of research papers, manuscripts, or other documents for publication and/or presentation.

Additional information

The Research Fellow will be situated at Brigham and Women's Hospital under the guidance and mentorship of Dr. Sophia Koo.

Qualifications

The ideal candidate should have received (or expect to receive soon) a MD or a PhD in a relevant biological field.

• Excellent English verbal and written communication skills
• Able to work both independently and in a team
• Interest in learning and troubleshooting new molecular biology techniques
• Familiarity with animal modeling of disease
• Excellent organizational and communication skills
• Excellent interpersonal skills and the ability to supervise and train staff effectively.
• Ability to prioritize tasks, set deadlines, and adapt to shifting priorities in response to changing deadlines and needs of the lab.

EDUCATION: Minimum Required: Doctoral Degree

Preferred: Doctoral Degree

Experience

Required: Recent MD or PhD graduate, 1+ years of experience in a research-related field required

Supervisory Responsibility

• May oversee research assistants, Technicians, Technologists, and Students.
• No authority to hire/promote/terminate

Working Conditions

• Work will be performed in the Thorn Research Building on the Brigham and Women's Hospital main campus, in Boston, MA.
• Additional Job Details (if applicable)

Pay and benefits

The compensation range for this role is between $71,750 - $81,179. Candidate experience is thoughtfully considered throughout the recruitment process, and those with significant experience may be considered for compensation above the starting range listed, as consistent with organizational guidelines and internal equity

• Years of experience
• 0 $71,750 - $73,544
• 1 $73,544 - $75,382
• 2 $75,382 - $77,267
• 3 $77,267 - $79,199
• 4+ $79,199 - $81,179
• Remote Type
• Onsite
• Work Location
• 20 Shattuck Street