Research Scientist, Applied Research
- Location
- San Francisco office
- Listed
- 6 days ago
About the Role
We are hiring research scientists to improve the real-world performance of our foundation models. The work involves planning targeted data generation campaigns, designing evals that accurately measure model performance, and formulating post-training recipes aimed at making models useful for real drug discovery problems.
We prioritize simple, robust methods over intricate solutions built for narrow problems. We particularly value researchers who can formalize messy biological problems using methods from other fields.
You will work in tight loops with our pre-training researchers, research engineers and science team. Your work will ship fast and you'll see your results reach real therapeutic programs across industry.
About You
- We look for technical depth paired with interest in the underlying biology.
- Biological background is not required.
- All of the following are positive signals:
- Published research in machine learning for protein, antibody, or small-molecule modelling.
- Fluency in the technical details of protein language, structure prediction, and design models (AlphaFold, RFDiffusion, ProteinMPNN, ESM, etc).
- Strong quantitative background (CS, math, or physics), particularly in probability, statistics, and machine learning.
- Deep software engineering expertise, with experience working in large codebases.
We are happy to bet on rising talent.
We Offer
- The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters.
- We protect and promote a culture of high velocity and ownership.
- We compensate our team accordingly.
About Chai Discovery
Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly GSK Pfizer Bristol Myers Squibb argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.
We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.
We value diverse perspectives and are ready to find greatness in unexpected places.
From Chai Discovery's careers page, first listed on Rolev.ai on November 4, 2026. Rolev.ai is not the employer.
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Common questions
Where is the Research Scientist, Applied Research job at Chai Discovery located?
This Research Scientist, Applied Research position at Chai Discovery is located in San Francisco office. Always check Chai Discovery's application page for specific state eligibility or relocation policies.
How do I apply for the Research Scientist, Applied Research position at Chai Discovery?
This listing links directly to Chai Discovery's Ashby application page. You can apply directly on Chai Discovery's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Ashby application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.