Research Technician

About the Opportunity

We are seeking a highly motivated and accountable Research Technician to join a fast-paced program developing automated, real-time microscope control systems for image-guided single-cell isolation and photoactivation.

The role focuses on building hardware and software systems that enable real-time, region-of-interest (ROI)-specific laser ablation and photoactivation, integrated directly into automated microscopy and spatial single-cell analysis workflows (Image-seq). This is a hands-on position requiring strong execution, ownership, and attention to detail in both real-time hardware control and optical instrumentation design.

Minimum Qualifications

• BS in Physics, Computer Engineering, Electrical Engineering, or a related field
• Hands-on experience with FPGA programming and hardware design (e.g., Xilinx/AMD Vivado or equivalent)
• Experience with real-time signal processing, hardware-software interfacing, and firmware development
• Demonstrated strong work ethic, accountability, and reliability
• Ability to work independently and manage multiple tasks efficiently

Preferred

• Experience interfacing real-time hardware control systems with microscopy or optical imaging platforms
• Background in optical instrumentation design or optical system integration
• Background in real-time data acquisition and processing (e.g., AXI Stream interfaces, USB protocols)
• Interest or prior exposure to biological or biomedical applications of engineering systems
• Experience with device firmware development for Windows-compatible systems

Key Responsibilities & Accountabilities

• Design, program, and optimize FPGA-based hardware platforms for real-time microscope control, including ROI-specific laser ablation and photoactivation
• Develop real-time signal processing pipelines to interface microscope hardware (scanning systems, detectors) with control electronics
• Contribute to the design and integration of optical instrumentation supporting real-time, image-guided targeting
• Integrate real-time hardware control systems with microscope acquisition software to enable fully automated workflows
• Develop and maintain device firmware and communication protocols (e.g., USB, AXI Stream) for hardware-software integration
• Support development of automated Image-seq and spatial single-cell analysis workflows, including real-time calibration, testing, and validation on biological samples
• Collaborate with lab members on applying real-time-controlled ablation/photoactivation systems to live-cell and tissue-based experiments
• Maintain rigorous documentation, troubleshoot hardware/software and optical issues, and clearly communicate results and technical progress

Additional information

This position is best suited for candidates who are highly driven, detail-oriented, and capable of executing at a high level in a demanding, interdisciplinary research environment spanning real-time engineering systems, optical instrumentation, and biology.

• Documents Required: Resume
• Cover Letter
• Position Type
• Research
• Additional Information

Northeastern University considers factors such as candidate work experience, education and skills when extending an offer.

Pay and benefits

Northeastern has a comprehensive benefits package for benefit eligible employees. This includes medical, vision, dental, paid time off, tuition assistance, wellness & life, retirement- as well as commuting & transportation.

Compensation Grade/Pay Type: 105H

Expected Hiring Range: $20.77 - $28.56

With the pay range(s) shown above, the starting salary will depend on several factors, which may include your education, experience, location, knowledge and expertise, and skills as well as a pay comparison to similarly-situated employees already in the role. Salary ranges are reviewed regularly and are subject to change.