Research Technician II- Pediatric Cancer Immunotherapy Development

About the role

SHIFT: Day (United States of America)

Seeking Breakthrough Makers

Children's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care-and your career.

CHOP does not discriminate on the basis of race, color, sex, national origin, religion, or any other legally protected categories in any employment, training, or vendor decisions or programs. CHOP recognizes the critical importance of a workforce rich in varied backgrounds and experiences and engages in ongoing efforts to achieve that through equally varied and non-discriminatory means.

A Brief Overview

This entry-level research technical role participates in a planned research projects by performing research protocols, experimental procedures and other laboratory tasks under direct supervision. May occasionally exercise minimal discretion and judgment in execution and interpretation of experiments, and of data derived.

This entry-level research technical role in Dr. John Maris' laboratory participates in a interdisciplinary translational research program under the direct supervision of Dr. Amber Hamilton. Projects will be focused on understanding the biologically relevant role of immunotherapeutic targets and developing pediatric cancer immunotherapies for neuroblastoma and Ewing sarcoma.

This role will perform research protocols, experimental procedures and other laboratory tasks under direct supervision. A successful candidate will exercise minimal discretion and judgment in execution and interpretation of experiments, and of data derived.

What you will do

• Performs routine tests / experiments under the direction of principal investigator, supervisor or other designee
• Performs rigorous research procedures on experimental samples as directed
• Examples of experiments will include maintaining neuroblastoma and Ewing sarcoma cell lines, cloning, CRISPRi, western blotting, flow cytometry, immunofluorescence, cytotoxicity and internalization assays, proteomics sample preparation and in-vivo studies.
• Performs research procedures on experimental samples as directed
• Records and checks experiments/ results for completeness and
• accuracy
• Performs calculations and maintains appropriate log and lab notebooks
• Performs tasks that require familiarity with fundamental techniques and lab equipment
• May assist with planning specific research protocols and procedures
• Maintains office, lab area, solutions, reagents, supplies and equipment, disposes of specimens, media and other materials (using appropriate procedures)
• Assists in care and maintenance of lab equipment
• May coordinate schedules of tests and procedures
• Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques
• Records results, organizes data and maintains lab notebook in an organized manner
• Compiles and helps analyze data, prepares charts, graphs, and results of studies as directed
• Conducts literary searches as directed
• Opportunities for professional development: attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques

Education Qualifications

• High School Diploma / GED Required
• Associate's Degree Preferred
• Bachelor's Degree Preferred

Experience Qualifications

• At least one (1) year of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Required
• At least two (2) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Preferred

Skills and Abilities

• Intermediate understanding of lab procedures, protocols, and equipment.
• Basic exposure to lab specific experiments / techniques and scientific analysis
• Excellent verbal and written communications skills
• Excellent organizational skills
• Solid critical thinking / problem-solving skills
• Solid analytical skills

Additional information

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must receive an annual influenza vaccine.

Salary Range

$43,900.00 - $54,800.00 Annually

Salary ranges are shown for full-time jobs. If you're working part-time, your pay will be adjusted accordingly.

At CHOP, we are committed to fair and transparent pay practices. Factors such as skills and experience could result in an offer above the salary range noted in this job posting. Click here for more information regarding CHOP's Compensation and Benefits.