Scientist 3, Lung Biology & Inflammation
- Location
- South San Francisco
- Listed
- 3 days ago
Why Genentech
We're passionate about delivering on Our Promise to improve the lives of patients and create healthier communities for all. We foster a culture of inclusivity, integrity and creativity while boldly pursuing answers to the world's most complex health challenges and transforming society.
The Opportunity
The Department of Immunology at Genentech is seeking a driven Scientist with deep expertise in lung biology and immunology to uncover novel therapeutic targets for respiratory diseases. In this role, you will lead research projects investigating the cellular and molecular mechanisms underlying the lung's response to injury, chronic inflammation, and repair.
- Lead projects investigating cellular and molecular mechanisms underlying lung injury, chronic inflammation, and tissue repair.
- Advance novel research-stage programs into early clinical development by generating robust proof-of-concept data.
- Utilize state-of-the-art technologies, including in vitro and in vivo models, to evaluate novel molecules and targeted delivery systems.
- Dissect the pathogenesis of inflammatory lung diseases and identify the mechanism of action (MOA) of breakthrough therapies.
- Drive pipeline research while actively exploring new biologies and pathways for target discovery.
- Facilitate fruitful, open collaborations across immunology, human genetics, biomarker discovery, and early clinical development.
- Present research findings effectively at intra- and inter-departmental scientific meetings.
Who you are
- PhD in immunology, stem cell biology, molecular biology, biochemistry, or a related field, with a demonstrated record of high-quality publications.
- Deep understanding of lung biology, particularly in chronic respiratory diseases, tissue remodeling/regeneration, or host-microbe interactions.
- Strong hands-on expertise in molecular biology, including cellular transfections, gene expression profiling, precision genome editing, and targeted RNA delivery technologies.
- Hands-on experience with primary cell isolation from human or mouse tissues, in vitro immunological assays, and multi-dimensional flow cytometry.
- Track record of independently designing, executing, troubleshooting, and interpreting complex experiments leading to first-author publication(s) in top-tier journals.
Preferred
- Proven experience with complex in vitro systems, including airway/alveolar organoids, air-liquid interface (ALI) 3D cultures, or organ-on-a-chip technologies.
- Experience with targeted therapeutic delivery of nucleic acid modalities (e.g., mRNA, siRNA, ASOs) using viral or non-viral vectors.
- Experience with computational data analysis, including scRNA-seq, spatial transcriptomics, or mining public/clinical datasets.
Location
- This role is based in South San Francisco and offers a hybrid schedule working 3 day per week on campus
- Relocation benefits are available for this posting
Pay and benefits
The expected salary range for this position based on the primary location of CA is $103,400.00 - 192,000.00 USD. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Equal opportunity and legal notices
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
From Roche's careers page, first listed on Rolev.ai on November 6, 2026. Rolev.ai is not the employer.
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Common questions
Where is the Scientist 3, Lung Biology & Inflammation job at Roche located?
This Scientist 3, Lung Biology & Inflammation position at Roche is located in South San Francisco. Always check Roche's application page for specific state eligibility or relocation policies.
How do I apply for the Scientist 3, Lung Biology & Inflammation position at Roche?
This listing links directly to Roche's Workday application page. You can apply directly on Roche's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Workday application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.