Strand Therapeutics
Healthcare & Life SciencesDirect Greenhouse career site

Scientist, Synthetic Biology

Pay
$120,000 – $132,000 per year
Location
Boston, MA · On-site
Job type
Full-time
Level
Mid-level
Experience
1+ year
Education
Doctorate
Listed
31 days ago

Skills & highlights for this role

  • molecular cloning
  • qPCR
  • mammalian cell culture
  • in vitro transcription of mRNA

Also useful

  • flow cytometry
  • image analysis
  • automation equipment

Stated benefits & perks

  • Health
  • Dental
  • Open pto

Job Summary

We are looking for a highly motivated and innovative candidate for the role of Scientist of Synthetic Biology. The ideal candidate will use fundamental biological design principles to build RNA-based genetic circuits to facilitate drug discovery and development. This is a fantastic opportunity to make a significant impact as a scientifically motivated self-starter capable of independently conceiving, conducting, and critically analyzing their own work with minimal supervision.

Primary Responsibilities

  • Design and develop synthetic genetic constructs to enable programmable, cell-type specific gene expression.
  • Build and test engineered circuits for desirable phenotypes in relevant cell systems in vitro thus validating predicted designs.
  • Plan experiments utilizing molecular techniques including molecular cloning, mammalian cell transfection, flow cytometry, ELISA, qPCR, Western blot etc.
  • Maintain proper records in electronic notebook and contribute to writing protocols
  • Communicate experimental methods and results to fellow team members and work closely with cross-functional teams.

Qualifications

  • PhD in Biomedical Engineering, Boinformatics, or requivalent required.
  • 1-2 years of professional research experience in industrial and/or academia required.
  • Ability to plan, design and execute experiments as part of a project, communicate findings to a diverse audience, and iterate on ideas for optimizing genetic circuit designs for a desired behavior.
  • Experience with cellular and molecular biology techniques like molecular cloning, qPCR, mammalian cell culture, and transfection required.
  • Prior experience with flow cytometry, image analysis, and automation equipment is a plus.
  • Hands-on experience with in vitro transcription of mRNA required.
  • Ability to quickly adapt to change and thrive in a dynamic and entrepreneurial early-stage environment.
  • A strong team player with excellent oral and written communication skills and a demonstrated ability to work independently.
  • Independently motivated, detail oriented and good problem-solving ability.
  • Excellent organizational skills and attention to detail.

Pay and benefits

Strand offers a fast-paced, entrepreneurial, team-focused small company environment. We also offer a top-notch benefits package (health, dental, life, open PTO, onsite lunch catering, commuter support and more) and work/life flexibility and integration. Being part of the Strand team allows you to become part of a small team that supports professional development while working together to meet Strand's goals.

Job Type: Full-time

Salary

$120,000 - $132,000 annually plus bonus and equity incentives

Pay Transparency Base Salary Range $120,000—$132,000 USD

Company Overview

Strand Therapeutics is a clinical-stage biotechnology company pioneering programmable mRNA therapeutics to unlock the full potential of genetic medicines. Strand is applying its proprietary Signal Stack platform, which integrates EverScript circular RNA, AmpliScript self-replicating RNA, SignalPath targeted delivery, and logic-driven SignalLock genetic circuits to enable precise control of therapeutic activity across tissues and cell types and overcome foundational limitations in targeting, durability, and safety.

Strand is advancing a pipeline with an initial focus on oncology and autoimmune disease. Its initial program, STX-001, an intratumorally delivered LNP-encapsulated self-replicating RNA expressing IL-12, has demonstrated preliminary evidence of systemic immune activation and anti-tumor activity in patients with advanced solid tumors who have progressed on prior therapies.

Building on this early clinical validation, intravenously delivered STX-003 is designed for tumor-targeted expression and avoidance of off-target expression. STX-003, which is expected to enter the clinic in mid-2026, has the potential to be a major step forward for the fields of genetic medicine and oncology.

Strand is also advancing STX-005, an in vivo CAR-T program designed to enable controlled, durable expression and repeat dosing. Founded by MIT synthetic biology pioneers, Strand has raised over $250 million and is headquartered in Boston, MA.

Become the next standout single strand!

Read the original posting

From Strand Therapeutics's careers page, first listed on Rolev.ai on October 10, 2026. Rolev.ai is not the employer.

How Rolev.ai helps with this application

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Common questions

What is the salary for the Scientist, Synthetic Biology role at Strand Therapeutics?

The Scientist, Synthetic Biology posting at Strand Therapeutics states compensation of $120,000 – $132,000 per year. It is listed as a full-time position. Final pay may depend on location, experience, and interview evaluation on Strand Therapeutics's official career site.

Where is the Scientist, Synthetic Biology job at Strand Therapeutics located?

This Scientist, Synthetic Biology position at Strand Therapeutics is located in Boston, MA (On-site). Always check Strand Therapeutics's application page for specific state eligibility or relocation policies.

What qualifications are required for Scientist, Synthetic Biology at Strand Therapeutics?

For the Scientist, Synthetic Biology role, Strand Therapeutics highlights 1+ year of relevant experience; a doctorate; experience with molecular cloning, qPCR, mammalian cell culture, in vitro transcription of mRNA. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.

How do I apply for the Scientist, Synthetic Biology position at Strand Therapeutics?

This listing links directly to Strand Therapeutics's Greenhouse application page. You can apply directly on Strand Therapeutics's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Greenhouse application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.