Senior Full-Stack Engineer

About the Role

Plenful is hiring Senior Full-Stack Engineers across all three of our product teams - 340B, Intake, and a new pod opening up a fresh area of pharmacy operations. You'll build features that pharmacy and health system teams use every day to run compliance-critical work, not internal tools only other engineers will ever see.

This is a senior role with real scope. You'll take a problem from a rough product idea to something live in production, and make sound technical calls along the way without needing every decision reviewed.

• Real ownership, fast. We're past the earliest startup stage but still small enough that one engineer can define how a whole workflow works for hundreds of health systems.
• Problems that matter. Pharmacy and health system teams are drowning in manual, compliance-critical work. What you ship directly changes how much of that work a human still has to do.
• AI as a daily tool, not a slogan. We expect you to use AI deliberately in how you build, and we're building AI into the product itself.
• Backing to build for the long term. Series B funding from investors including Bessemer Venture Partners, Notable Capital, and Danaher co-founder Mitchell Rales gives us the runway to invest in the engineering foundation, not just ship quick fixes.

What You’ll Do

• Build and ship full-stack features end to end, from the database to the UI, for workflows like 340B compliance, intake, rebate management, and claims reconciliation.
• Partner directly with product managers and pharmacy operations experts to understand what pharmacy teams actually need, not just what's in the ticket.
• Own what you ship: design it, build it, test it, deploy it, and support it in production.
• Make sound tradeoffs between speed and durability as Plenful scales its platform to serve more health systems.
• Contribute to the technical foundation of the platform, including how AI gets embedded into product workflows.
• Use AI tools deliberately as part of how you work, not just how you demo.
• Review code, weigh in on design docs, and help raise the technical bar across the team.

You May Be a Fit If

• You've spent 7+ years in professional software engineering, working across the stack.
• You're proficient in JavaScript and TypeScript, with working proficiency in Python.
• You've built customer-facing products - not primarily internal tooling or developer platforms.
• You're comfortable moving across layers of the stack instead of staying in one.
• You've worked in a fast-moving, high-growth environment where priorities shift as the product and customer base scale.
• You have strong instincts for what "production-ready" means in a compliance-critical, enterprise healthcare context.
• You communicate clearly with product, design, and non-technical stakeholders.
• You're open to being based in San Francisco (hybrid, in-office Mondays and Wednesdays) or Chicago (remote).
• Bonus points for experience with Java or Ruby (if you don't know Python, you're willing to learn it), healthcare or pharmacy experience, or a track record at startups that scaled from 0 to 1 and beyond.

Benefits & Perks

• Healthcare Coverage - Full medical, dental, and vision insurance for you and participation for your family
• 401(k) with Company Match - Plenful matches 50% of your first 3% contributed
• Equity - Every full-time employee shares in our success
• Unlimited PTO - Take the time you need, when you need it
• Daily Lunch Stipend - $100/week to cover your midday meals
• Wellness Stipend - $100/month to support your health and well-being
• Commuter Benefits - $100/month for SF and NYC-based employees
• Parental Leave - Paid leave to support growing families