Senior Legal Counsel, Clinical

What you will do

• Draft, review, negotiate and execute a wide variety of clinical research agreements, including Clinical Trial Agreements (CTA), Master Service Agreements (MSA), investigator agreements, site contracts, laboratory service agreements, clinical supply agreements and patient and subject-related agreements.
• Serve as the primary, day-to-day legal business partner embedded directly alongside the Clinical Development team.
• Partner with internal stakeholders to establish, scale and optimise standardised clinical contracting playbooks and template libraries to streamline study start-up timelines.
• Identify, manage and mitigate legal, regulatory, intellectual property, data privacy, and compliance risks across global clinical operations.
• Collaborate closely with cross-functional Legal & Business Operations colleagues (IP, Corporate Legal and Privacy) to ensure end-to-end alignment on trial governance and data rights.
• Manage outside counsel and clinical transactions legal budget.
• Proactively evaluate, pilot, and embed cutting-edge AI technologies into the clinical contracting lifecycle to accelerate legal operations.

Skills and qualifications

• J.D. or equivalent law degree with active U.S. state bar admission in good standing (Massachusetts Bar or eligible for in-house registration in MA).
• Substantial, direct experience structuring, drafting, and negotiating complex clinical trial agreements, Master Service Agreements (MSA), investigator agreements, site contracts, laboratory service agreements, clinical supply agreements and patient and subject-related agreements.
• Experience gained either within a biotechnology/pharmaceutical in-house legal department or a specialised life sciences law firm practice.
• Expert knowledge of clinical trial execution, CRO outsourcing models and regulatory guidelines (GCP/ICH).
• Proven ability to work autonomously and prioritise a high volume of transactions in a fast-paced, high-growth environment.
• Strong collaborative mindset with exceptional stakeholder communication skills, tailored to embedding directly with scientific, medical and clinical operations teams.
• Familiarity with global and multi-jurisdictional clinical trial contracting landscapes (US, UK, and EU regulatory frameworks).
• Experience navigating clinical data rights and IP provisions at the intersection of computational biology, data-intensive research, or AI-driven platforms.

Culture and values

• We are guided by our shared values.
• It's not about finding people who think and act in the same way.
• These values help to guide our work and will continue to strengthen it.

Thoughtful

Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.

Brave

Brave at Iso is about fearlessness, but it's also about initiative and integrity. The scale of the challenge demands nothing less.

Determined

• Determined at Iso is the way we pursue our goal.
• It's a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it.
• Because disease won't wait, so neither should we.

Together

• Together at Iso is about connection, collaboration across fields and catalytic relationships. It's knowing that transformation is a group project, and remembering that what we're doing will have a real impact on real people everywhere.
• Creating an extraordinary company

• We believe that to be successful we need a team with a range of skills and talents.
• We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive.
• We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.

Hybrid working

It's hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you're in). If you have additional needs that would prevent you from following this hybrid approach, we'd be happy to talk through these if you're selected for an initial screening call.

• Please note that when you submit an application, your data will be processed in line with our privacy policy.
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