Senior Machine Learning Scientist
- Location
- South San Francisco, CA · On-site
- Job type
- Full-time
- Level
- Director
- Listed
- 31 days ago
Skills & highlights for this role
- machine learning
- deep learning
- statistics
Also useful
- single-cell genomics
- foundation models
Your role
With Tahoe-100M, we solved one of the fundamental bottlenecks in building a virtual model of the cell: generating massive, perturbation-rich, single-cell datasets that capture real biological causality. With Tahoe-x1, we removed the second bottleneck: creating a modern platform for rapid iteration on model architectures and designs in a cost-efficient manner and at scale. At Tahoe, we embody a simple philosophy: build in the open, shoot for the moon, and we’re looking for people who want to push the frontier of what’s possible.
As a Senior Machine Learning Scientist, you will play a leading role in designing the next generation of foundation models of gene regulatory networks powered by Tahoe’s large scale single-cell datasets such as Tahoe-100M and beyond. This role is well-suited for someone with a strong background in machine learning and statistics, and an interest in applying cutting-edge breakthroughs in ML to meaningful problems in drug discovery. We are looking for non-incremental thinkers with the skills to help build models that can make a real impact on drug discovery.
About Tahoe Therapeutics
Tahoe Therapeutics is a biotechnology company pioneering a fundamentally new approach to drug discovery, one that begins with the biology of real patients. Our Mosaic platform is the first to make in vivo data generation scalable, with single-cell resolution, allowing us to map how drugs affect patient-derived cells in the body across a wide range of biological contexts.
We are building the world’s largest in vivo single-cell perturbation atlas and using it to train multimodal foundation models that learn the context-dependent nature of gene function, disease progression, and drug response.By combining cutting-edge machine learning with the most biologically relevant datasets ever assembled in drug discovery, our mission is to find better drugs, faster and bring them to more patients who need them.
From Tahoe Therapeutics's careers page, first listed on Rolev.ai on October 10, 2026. Rolev.ai is not the employer.
How Rolev.ai helps with this application
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Common questions
Where is the Senior Machine Learning Scientist job at Tahoe Therapeutics located?
This Senior Machine Learning Scientist position at Tahoe Therapeutics is located in South San Francisco, CA (On-site). Always check Tahoe Therapeutics's application page for specific state eligibility or relocation policies.
What qualifications are required for Senior Machine Learning Scientist at Tahoe Therapeutics?
For the Senior Machine Learning Scientist role, Tahoe Therapeutics highlights experience with machine learning, deep learning, statistics. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.
How do I apply for the Senior Machine Learning Scientist position at Tahoe Therapeutics?
This listing links directly to Tahoe Therapeutics's Lever application page. You can apply directly on Tahoe Therapeutics's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Lever application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.