Senior Medical Program Manager (MPM) - One Medical Early Assets

About the role

Location: Cambridge, MA

About the Job

The MPM will provide program management expertise, team and portfolio management, and strategic operational support across the One Medical early asset portfolio, enabling integrated medical inclusion from discovery through proof of concept.

This individual will work closely with the Medical Program Lead (MPL), Early Asset Global Medical Leads (GMLs), and Global Medical Teams (GMTs), both internally and with alliance partners where applicable, to ensure medical knowledge and insights flow seamlessly across the early-development value chain, forging aligned partnerships across R&D.

The position sits within the NextGen Immunology (NGI) team but carries responsibility across One Medical SPC and Gen Meds. Working in a matrix environment, the MPM drives strategic direction and operational execution, ensuring teams are empowered to innovate boldly together across the early medical lifecycle.

Join the engine of Sanofi's mission - where deep immunoscience meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions.

Main Responsibilities

• Provide program management expertise, team and portfolio management, and strategic operational support across the One Medical early asset portfolio
• Enable integrated medical inclusion across early-stage assets from discovery through proof of concept
• Drive strategic direction and operational execution, ensuring the GML has line of sight across R&D to deliver impact in the Global Project Teams (GPTs) from M2
• Position Medical to co-lead Disease Area Strategies in partnership with R&D
• Forge strategic partnerships and shared governance with the TMU ECET Program, CSU eProtocol, and Patient Driven Medicine Development
• Plan, Coordinate and Co-partner on driving the early iEGP (Integrated Evidence Generation Plan) roadmap at both disease area and asset level
• Drive evidence generation prioritization in partnership with the GML
• Design, coordinate, and co-lead a Global Medical Team (GMT) system that ensures resource efficiency and a strong matrixed network across global medical, local medical, and cross-functional partners early in the medical lifecycle
• Establish a framework for operationalizing medical strategy, tactics, and clinical investment planning for early medical and budget needs as assets advance through the lifecycle, for use by asset and disease area teams
• Manage portfolio and operational level activities via the harmonized Program Management Tool used across the MPM organization
• Ensure workflows and processes are efficient and compliant with internal SOPs and external guidelines

Basic requirements

• Bachelor's degree in Life Sciences, Biomedical Sciences, Pharmacy, Health Sciences, or a related scientific discipline required. Advanced scientific degree (MS, PharmD, PhD, MD) preferred; MBA or equivalent business qualification is a plus.
• Minimum 5 years of project/program management, portfolio management, or related experience within the biopharmaceutical, biotechnology, healthcare, clinical research, or scientific environment, with experience supporting cross-functional teams and complex initiatives.
• Background in the biopharmaceutical or pharmaceutical industry with direct experience in project/program management; scientific background and Medical Affairs experience preferred.
• Ability to lead projects and translate strategy into tactical plans and reusable frameworks
• Thorough understanding of project/program management techniques and methodology
• Ability to foster teamwork and collaboration coordinating cross-functional teams in a matrix environment
• Ability to manage projects end to end with minimum supervision
• Ability to establish and provide frequent reporting dashboards with key metrics utilizing harmonized methodologies
• Strong interpersonal and communication skills with the ability to effectively interface across all levels of the organization
• Ability to multitask and maintain tight timelines and priorities in a highly professional manner
• Excellent knowledge of MS Office; working knowledge of program/project management software

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.
• #GD-SA
• #LI-SA
• #LI-Onsite
• #vhd
• Pursue progress, discover extraordinary

Additional information

Better is out there. Better medications, better outcomes, better science. But progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people.

Sanofi US endeavours to make our career center accessible to any and all users. If you are experiencing difficulty and need assistance applying online, please call 1-866-SANOFI2 () or

Pay and benefits

The salary range for this position is: $122,250.00 - $176,583.33

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.