Senior Scientist - Automation

About the role

• Work Schedule
• Standard (Mon-Fri)
• Environmental Conditions
• Office

About the role

Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission - to enable our customers to make the world healthier, safer, and cleaner.

Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to demonstrate the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.

A day in the Life

• Conduct experiments using liquid handling automation and apply the appropriate analytical techniques such as surface plasmon resonance, capillary gel electrophoresis, cell-based bioassays, and others
• Successfully apply the automation assets for rapid screening and/or development to reduce design selection risks and enhance product design across all phases of development.
• Troubleshoot and systematically evaluate and assess root causes of errors in the laboratory, identify inefficiencies arising from human, software, hardware, firmware, and/or chemical sources
• Organize, evaluate, and present data in an effective and scientific manner through discussions, presentations and reports
• Contribute to the development of new automation approaches and knowledge within the global automation organization.
• Ensure the local capability to rapidly demonstrate existing laboratory automation in order to dramatically reduce the time to address design selection issues with drug development.
• Write protocols for new automation workflows using robotic-specific software for laboratory instruments e.g., Agilent HPLC, Unchained Labs, Mettler Toledo, Chemspeed, Andrew Alliance, and Hamilton.

Knowledge, Skills and Abilities

• Solid understanding and knowledge of general biology, chemistry and separation science
• Demonstrated product development experience across multiple projects in pharmaceutical development environment, with evidence of achieving product deliverables within disciplinary expertise.
• Broad knowledge of analytical method development in support of new chemical entity (NCE) development
• Proficient in and demonstrates highly effective oral and written communication skills.
• Proficient in operating automated liquid-handling systems (i.e. Hamilton)
• Great teammate and ability to work in a matrix environment.
• Proven ability to troubleshoot and diagnose problems in analytical platforms.
• Demonstrated ability to collaborate with multiple internal and external groups to successfully deliver projects.
• High learning agility - has the ability and willingness to deal effectively with first-time situations or changing conditions.
• Knowledge and experience with statistical design of experiments and analysis of results.
• Demonstrated ability to integrate, test, and troubleshoot analytical instrumentation.
• Full understanding of laboratory requirements, PPD & client SOPs, ICH guidelines, USP requirements and FDA guidance.
• Ability to apply Microsoft Excel, PowerPoint, and Word to perform tasks
• Proficiency in technical operating systems
• Proven ability in technical writing skills
• Time management and project management skills
• Ability to work in a collaborative work environment within a team.

Education

• BS degree with 4+ years of experience, MS with 2+ years of experience, PhD with 0-2 years of experience in an appropriate subject area