Senior / Staff Software Engineer
- Location
- San Mateo, CA · On-site
- Job type
- Full-time
- Level
- Lead / Staff
- Experience
- 5+ years
- Education
- Bachelor's degree
- Listed
- 23 days ago
Skills & highlights for this role
- Python
- backend systems
- GCP
- production infrastructure
Stated benefits & perks
- Unlimited pto
Role Description
This is a full-time on-site role for a Senior or Staff Software Engineer (Technical Lead) located in the San Francisco Bay Area.
In this role, you will lead the design and development of core systems that power autonomous research agents. You’ll be responsible for building reliable backend infrastructure and production systems that support large-scale AI experimentation and research workflows.
We are looking for engineers who have owned complex projects end-to-end, contributed to system architecture, and helped guide small teams of engineers through delivery. You should be comfortable writing high-quality code, producing clear design documents, and making thoughtful technical decisions that shape how systems evolve over time.
You will work closely with both engineers and researchers to translate experimental ideas into robust production systems.
Responsibilities
- Lead the design and implementation of core backend and infrastructure systems
- Own projects from architecture and design through production deployment
- Write clear technical design documents and drive engineering decisions
- Build and maintain 24/7 production systems supporting autonomous research agents
- Partner closely with research teams to productionize experimental workflows
- Guide and collaborate with engineers on system design and implementation
- Improve system reliability, scalability, and observability
- Help shape the technical direction of the platform
Qualifications
- Experience leading complex engineering projects or technical initiatives
- Experience acting as a technical lead or guiding small teams of engineers
- Strong software design and architecture skills
- Demonstrable experience writing clear technical design documents
- Strong experience with Python
- Experience building or operating backend or production infrastructure
- Experience working in 24/7 production environments
- Experience with Google Cloud Platform (GCP) or similar cloud infrastructure
- Strong understanding of software evolution, maintainability, and system design tradeoffs
- Ability to collaborate effectively with both engineers and researchers
- Bachelor’s degree in Computer Science, Mathematics, or a related field
- Strong candidates will typically have 5+ years of experience building and operating production software systems, including ownership of projects from design through deployment
Benefits & Perks
- Our comp is competitive against major LLM frontier lab packages
- Unlimited PTO and flexible working arrangements
- Conference attendance and publication support
Company Description
At Autoscience Institute, we automate AI research. Recently, we announced the first AI agent to autonomously create peer-reviewed literature (ICLR 2025) and the first AI system to win a Kaggle medal. We are passionate about pushing the boundaries of artificial intelligence and contributing to groundbreaking advancements in the field.
Our Culture
We're a team of passionate researchers and engineers working to automate scientific discovery. We believe in the power of AI to accelerate scientific discovery and are committed to responsible AI development.
From Autoscience's careers page, first listed on Rolev.ai on October 17, 2026. Rolev.ai is not the employer.
How Rolev.ai helps with this application
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Common questions
Where is the Senior / Staff Software Engineer job at Autoscience located?
This Senior / Staff Software Engineer position at Autoscience is located in San Mateo, CA (On-site). Always check Autoscience's application page for specific state eligibility or relocation policies.
What qualifications are required for Senior / Staff Software Engineer at Autoscience?
For the Senior / Staff Software Engineer role, Autoscience highlights 5+ years of relevant experience; a bachelor's degree; experience with Python, backend systems, GCP, production infrastructure. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.
How do I apply for the Senior / Staff Software Engineer position at Autoscience?
This listing links directly to Autoscience's Ashby application page. You can apply directly on Autoscience's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Ashby application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.