Sr Director, Commercial Operations
- Pay
- $224,000 – $289,000 per year
- Location
- South San Francisco, CA · On-site
- Job type
- Full-time
- Level
- Director
- Experience
- 10+ years
- Education
- Bachelor's degree
- Listed
- 30 days ago
Skills & highlights for this role
- Salesforce
- sales planning and forecasting
- pipeline management
- commercial analytics
Stated benefits & perks
- Bonus
- Equity
What You'll Be Doing
- Manage Commercial Operations team consisting of Customer Master Data Specialist, Process Improvement, Sales Operation, Business Management, and Project Management Teams.
- Lead cross-functional process improvements projects (pricing strategy, discount governance, contracting) and implement new process (i.e., multi-currency and Distributor Flow enhancement).
- Create a center of excellence for Commercial Reporting.
- Develop and implement strategic plans to improve performance in all aspects of Commercial Operations.
- Partner with Sales and Marketing to evaluate new technology that could improve sales and marketing operations.
- Structure, develop, and implement scalable process and procedures to implement an insights-driven commercial approach and top-tier Customer engagement.
- Participate in hiring, training, and ongoing coaching of leadership staff to ensure execution of sales performance.
- Conducts sales performance reviews on a regular schedule.
- Partners with HR in all employee relation activities including Process Improvement plans, coaching, steps of discipline and termination.
- Determining staffing needs based on workload requirements and recruiting and hiring staff accordingly.
- Available as resource and mentor to leadership and team members.
- Assess whether current sales strategies are sufficient for meeting company sales goals.
- Support lead governance and handoff process from Digital Marketing, ISS, and Field Sales to ensure smooth handoff and reporting capability.
- Collaborate cross-organizationally to create a robust performance and opportunity metrics that the Executive Team will use to make informed decisions surrounding commercial and go-to-market strategy.
What You'll Bring to the Team
- Degree in Biology, Biochemistry, or a related field
- 10+ years of progressive commercial and technical experience in the life sciences/biotech space
- 5+ years in managerial and supervisory roles leading cross-functional teams.
- Demonstrated expertise in sales planning, forecasting, pipeline management, CRM systems (Salesforce), commercial analytics, and process improvement within a fast-paced B2B environment.
Additional information
Twist Bioscience is a leading synthetic biology and genomics company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The core of the platform is a proprietary technology that pioneers a new method of manufacturing synthetic DNA by "writing" DNA on a silicon chip. Twist uses this platform to serve customers working in healthcare, agriculture, industrial chemicals, academic research and beyond, with products spanning synthetic genes and oligos, NGS target enrichment, and antibody discovery and development services.
Pay and benefits
The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.
San Francisco Bay Area Pay Range $224,000—$289,000 USD
About Twist Bioscience
Twist Bioscience is looking for a Director, Commercial Operations to lead, scale, and optimize key operating disciplines across our global commercial organization. In this role, you will lead cross-functional process improvements, oversee sales and project management operations, establish commercial reporting standards, and partner with executive leadership to drive scalable growth and an insights-driven sales approach.
From Twist Bioscience's careers page, first listed on Rolev.ai on October 10, 2026. Rolev.ai is not the employer.
How Rolev.ai helps with this application
Rolev.ai is a job search and application tool for US job seekers. For this Sr Director, Commercial Operations role at Twist Bioscience, it shows how your resume fits, tailors your resume to the posting, and prepares the application for you to review.
See how you fit
Openings from employer career sites are ranked against your whole resume—and searchable inside Claude, ChatGPT, and Cursor via Rolev.ai MCP.
Tailor without inventing
Every change to your resume is checked against your original. New experience goes in only with your yes—zero fabricated claims.
Draft the full kit
Tailored and Full Match resumes, role-specific cover letters, and answers to employer screening questions are prepared in seconds.
1-Click Extension Autofill
The Chrome extension fills the employer's Greenhouse, Workday, Lever, or Ashby form in 1 click. You review it and press Submit.
Common questions
What is the salary for the Sr Director, Commercial Operations role at Twist Bioscience?
The Sr Director, Commercial Operations posting at Twist Bioscience states compensation of $224,000 – $289,000 per year. It is listed as a full-time position. Final pay may depend on location, experience, and interview evaluation on Twist Bioscience's official career site.
Where is the Sr Director, Commercial Operations job at Twist Bioscience located?
This Sr Director, Commercial Operations position at Twist Bioscience is located in South San Francisco, CA (On-site). Always check Twist Bioscience's application page for specific state eligibility or relocation policies.
What qualifications are required for Sr Director, Commercial Operations at Twist Bioscience?
For the Sr Director, Commercial Operations role, Twist Bioscience highlights 10+ years of relevant experience; a bachelor's degree; experience with Salesforce, sales planning and forecasting, pipeline management, commercial analytics. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.
How do I apply for the Sr Director, Commercial Operations position at Twist Bioscience?
This listing links directly to Twist Bioscience's Greenhouse application page. You can apply directly on Twist Bioscience's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Greenhouse application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.