Iambic Therapeutics, Inc.
Direct Ashby career site

Sr Manager, Enterprise Business Systems

Location
San Diego HQ
Listed
4 days ago

Job Summary

We are seeking an experienced and results-driven Sr Manager, Enterprise Business Systems to join our growing IT team. This role will oversee the implementation, configuration, maintenance, and support of business-critical applications across the organization, with primary focus on the systems that run our General & Administrative (G&A) functions: Finance and Accounting, People/HR, Legal and Compliance, and Facilities, IT Operations, and Business Operations.

The Sr. Manager, Enterprise Business Systems will collaborate with leaders across each G&A function to optimize workflows, troubleshoot system issues, and drive continuous improvement in business processes. This role ensures that business applications operate efficiently, securely, and meet the evolving strategic and tactical needs of the company.

This position will be based out of our San Diego Headquarters.

Key Responsibilities

  • Apply deep working knowledge of enterprise software across the G&A landscape to implement, integrate, and maintain business applications supporting:
  • Finance and Accounting (ERP, budget forecasting & tracking, procurement, invoicing & expenses),
  • People/HR (HRIS, payroll, talent acquisition, learning management)
  • Legal and Compliance (contract lifecycle management, e-signature, entity management)
  • Facilities/Operations (service management, asset and space management).
  • Ensure application security, role-based access controls, segregation of duties, and compliance with company policies across all G&A systems.
  • Perform regular system updates, patches, and upgrades to maintain performance and security.
  • Liaise with software vendors and service providers for application support and upgrades.
  • Integrate business applications with other systems and third-party tools and assist in data migrations, imports, and exports between systems.

Qualifications

  • Bachelor’s degree in Information Technology, Computer Science, Business Administration, or a related field.
  • 12 years IT experience, with 8+ years administering cross-functional business applications spanning multiple G&A functions, life sciences experience preferred
  • Experience supporting financial processing and audit controls for Sarbanes-Oxley compliance, as well as the access, confidentiality, and retention requirements of HR and Legal systems.
  • Working knowledge of data privacy and associated regulatory requirements such as GDPR, CCPA, HIPAA, and Transparency Reporting.
  • Strong experience implementing, maintaining and improving Finance, Procurement, HR, Legal and Compliance systems such as NetSuite, Adaptive, Procurify, HRIS, Ashby ATS, DocuSign, and Ironclad preferred
  • Experience managing SaaS vendor relationships, contracts, renewals, and license optimization across a portfolio of business applications.
  • Experience in system implementation, data migration, or process automation.
  • Excellent communication and collaboration abilities with strong analytical and problem-solving skills.
  • Prior experience with IT service management, identity and access management (SSO, SCIM, provisioning), and corporate IT or facilities systems preferred
  • Experience with reporting methodologies and business metrics preferred
  • Project management experience or certifications (e.g., PMP, ITIL, Agile) preferred

Mission & Core Values

Our mission is to deliver better medicines through innovations in AI-based discovery technologies. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.

Pay and Benefits

We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.

About Iambic Therapeutics

Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters.

The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need.

Read the original posting

From Iambic Therapeutics, Inc.'s careers page, first listed on Rolev.ai on November 6, 2026. Rolev.ai is not the employer.

How Rolev.ai helps with this application

Rolev.ai is a job search and application tool for US job seekers. For this Sr Manager, Enterprise Business Systems role at Iambic Therapeutics, Inc., it shows how your resume fits, tailors your resume to the posting, and prepares the application for you to review.

  • See how you fit

    Openings from employer career sites are ranked against your whole resume—and searchable inside Claude, ChatGPT, and Cursor via Rolev.ai MCP.

  • Tailor without inventing

    Every change to your resume is checked against your original. New experience goes in only with your yes—zero fabricated claims.

  • Draft the full kit

    Tailored and Full Match resumes, role-specific cover letters, and answers to employer screening questions are prepared in seconds.

  • 1-Click Extension Autofill

    The Chrome extension fills the employer's Greenhouse, Workday, Lever, or Ashby form in 1 click. You review it and press Submit.

Common questions

Where is the Sr Manager, Enterprise Business Systems job at Iambic Therapeutics, Inc. located?

This Sr Manager, Enterprise Business Systems position at Iambic Therapeutics, Inc. is located in San Diego HQ. Always check Iambic Therapeutics, Inc.'s application page for specific state eligibility or relocation policies.

How do I apply for the Sr Manager, Enterprise Business Systems position at Iambic Therapeutics, Inc.?

This listing links directly to Iambic Therapeutics, Inc.'s Ashby application page. You can apply directly on Iambic Therapeutics, Inc.'s site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Ashby application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.