Staff IT Systems Engineer, Endpoints
- Pay
- $140,000 – $172,667 per year
- Location
- Cambridge, MA USA
- Job type
- Full-time
- Level
- Lead / Staff
- Listed
- 23 days ago
Skills & highlights for this role
- Jamf
- Intune
- Python
- PowerShell
- CI/CD
Also useful
- Workspace ONE
- EDR
- zero-touch provisioning
Your Impact at LILA
Lila is hiring a Staff IT Systems Engineer, Endpoints to own the architecture and roadmap for endpoint management across the company. This role sits within IT & Security and supports the technology every scientist, engineer, and employee relies on, including laptops, mobile devices, specialized research compute, endpoint security, and device trust.
We treat endpoint management as a software engineering discipline. Configuration, policy, remediation, and fleet operations should move through code, CI/CD, staged rollout, observability, and automated rollback. This is a hands-on staff-level role for someone who can set technical standards, build missing tooling, mentor engineers, and lead cross-functional initiatives across IT, Security, Research Computing, and Lab Operations.
As Lila scales its workforce and physical footprint, endpoint systems need to become more automated, secure, auditable, and seamless. The right person will help employees and scientists become productive faster while reducing device risk, operational noise, and manual toil.
What You'll Be Building
- Own the architecture and roadmap for Lila's endpoint fleet across macOS, Windows, Linux, mobile devices, and specialized research or lab computing endpoints.
- Define standards for endpoint configuration, policy, remediation, observability, and rollout practices across the IT & Security team.
- Drive configuration-as-code adoption for MDM policies, profiles, scripts, staged rollouts, canary groups, and automated rollback.
- Design zero-touch provisioning workflows so devices arrive encrypted, configured, compliant, and productive out of the box.
- Partner with Security to integrate endpoint posture, device trust, vulnerability data, EDR, and Zero Trust access controls.
- Build automation and internal tooling using scripts, APIs, CI/CD, and AI-assisted engineering practices to reduce manual toil.
- Improve vulnerability and patch management through telemetry, dashboards, drift detection, and auditable compliance workflows.
- Support specialized computing environments, including research workstations, lab-adjacent systems, VDI, managed browsers, and remote-access patterns where appropriate.
- Serve as a technical escalation point for complex endpoint issues and mentor engineers across IT and Security.
- Partner across Security, Legal, HR, Research Computing, and Lab Operations to protect sensitive IP while keeping the employee experience seamless.
What You'll Need to Succeed
- Deep experience in IT systems engineering, endpoint engineering, infrastructure, or platform engineering, with staff-level technical ownership.
- Strong experience with modern MDM or UEM platforms such as Jamf, Intune, Workspace ONE, or similar tools.
- Experience managing endpoint configuration through code, automation, version control, staged rollout, or CI/CD practices.
- Strong systems knowledge across macOS and Windows endpoint environments.
- Ability to build and maintain automation using Python, Bash, PowerShell, APIs, or similar tooling.
- Experience using AI-assisted engineering, LLM APIs, internal copilots, or agentic automation to reduce operational toil in IT, endpoint, infrastructure, or platform operations.
- Experience partnering with Security on endpoint hardening, device trust, vulnerability management, EDR, or Zero Trust initiatives.
- Strong troubleshooting ability across endpoint, identity, network, application, and user-experience boundaries.
- Track record mentoring engineers, setting technical standards, and leading cross-functional technical initiatives.
- Clear written and verbal communication skills with the ability to influence technical decisions across teams.
Bonus Points For
- Experience supporting scientific, research, lab, OT, or high-performance computing environments.
- Familiarity with Okta, SAML, SCIM, device trust, SASE, EDR, or cloud access patterns.
- Experience with AWS, GCP, cloud-native infrastructure, or cloud-based endpoint telemetry workflows.
- Experience with open-source endpoint tooling such as osquery, Fleet, Munki, or similar tools.
- Experience building VDI, managed browser, call center, or contact center computing environments.
- Proficiency in Go, Swift, or another language used for custom endpoint tooling.
- Experience in a regulated, IP-sensitive, biotech, life-sciences, or research environment.
Compensation
We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.
U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.
International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.
Expected Base Salary Range $140,000—$172,667 USD
We're All In
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
A Note to Agencies
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.
About LILA
Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
Equal opportunity and legal notices
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
From Lila Sciences's careers page, first listed on Rolev.ai on October 17, 2026. Rolev.ai is not the employer.
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Common questions
What is the salary for the Staff IT Systems Engineer, Endpoints role at Lila Sciences?
The Staff IT Systems Engineer, Endpoints posting at Lila Sciences states compensation of $140,000 – $172,667 per year. It is listed as a full-time position. Final pay may depend on location, experience, and interview evaluation on Lila Sciences's official career site.
Where is the Staff IT Systems Engineer, Endpoints job at Lila Sciences located?
This Staff IT Systems Engineer, Endpoints position at Lila Sciences is located in Cambridge, MA USA. Always check Lila Sciences's application page for specific state eligibility or relocation policies.
What qualifications are required for Staff IT Systems Engineer, Endpoints at Lila Sciences?
For the Staff IT Systems Engineer, Endpoints role, Lila Sciences highlights experience with Jamf, Intune, Python, PowerShell, CI/CD. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.
How do I apply for the Staff IT Systems Engineer, Endpoints position at Lila Sciences?
This listing links directly to Lila Sciences's Greenhouse application page. You can apply directly on Lila Sciences's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Greenhouse application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.