Senior Program Manager, Client Delivery

Vivodyne creates human data before clinical trials.

We accelerate the successful discovery, design, and development of human therapeutics by testing on large, lab-grown human organ tissues at massive scale, driving technological advancement at the convergence of novel biology, robotics, and AI.

We identify and validate new therapeutic targets and de-risk new therapeutic assets by producing clinically translatable multi-omic data from our proprietary, physiologically-realistic human organ tissues at unprecedented scale, speed, and quality. This enables us to produce more human data than all clinical trials in the U.S. combined.

We're financially backed by some of the most selective and successful venture funds, and we have already partnered with a majority of the top 10 multinational pharmaceutical companies to discover and develop better, safer drugs and dramatically reduce the burden of animal testing.

Role

Vivodyne is seeking a Senior Program Manager, Client Delivery to lead the operational delivery of complex client programs across Vivodyne's scientific, technical, and commercial teams. This person will serve as a primary internal coordinator and, for assigned accounts, a client-facing program lead. They will translate work plans into executable schedules, maintain clear communication, surface risks early, and ensure delivery commitments remain visible across teams.

This is a full-time, on-site role based in San Francisco, working closely with a bicoastal delivery team, with occasional travel to our Philadelphia site.

Responsibilities

Client Engagement & Delivery

• Own end-to-end delivery for a portfolio of complex client programs, accountable for delivering against agreed scope, timelines, budget, and client commitments from kickoff and work-plan alignment through execution, data delivery, closeout, and subsequent phases. Programs may span multiple technical workstreams, sites, external partners, and extended timelines.
• Act as a consistent client-facing program lead for assigned accounts, establishing communication cadence, coordinating key decisions and follow-ups, providing clear status updates, and raising schedule or deliverable risks early.
• Lead client kickoff and delivery planning, ensuring work plans, dependencies, ownership, collaboration workflows, and legal or operational prerequisites are aligned before execution.
• Coordinate data and documentation delivery, establishing clear expectations, ownership, and timelines for technical reports, assay and methods documentation, data packages, presentations, and client communications.

Internal Stakeholder Alignment & Resource Management

• Build and maintain integrated program plans covering milestones, dependencies, study schedules, resources, owners, risks, and delivery dates, providing practical execution guidance when programs compete for shared resources.
• Coordinate cross-functional execution across biology, operations, microfabrication, hardware/software, data analysis, business development, and leadership. Translate program objectives and requirements into clear internal context, decisions, and next steps.
• Manage scope, capacity, and schedule trade-offs, identifying constraints across resource availability, product readiness, staffing, materials, technical development, client requirements, and operational capacity; facilitate decisions and communicate their implications.
• Run portfolio-level delivery operating rhythms, including weekly reviews and leadership updates that surface priorities, risks, decisions, and cross-team dependencies.
• Maintain a reliable system for program and portfolio management, ensuring project plans, ownership, dependencies, risks, and status remain current and visible across teams.

Strategy & Operational Excellence

• Coordinate internal R&D and tissue roadmap execution in partnership with biology and product leads, translating scientific priorities into executable plans, milestones, and timelines. Balance internal model and capability development with client delivery commitments.
• Partner with BD and leadership on feasibility, resourcing, pricing, and delivery planning for prospective and expanding client work, helping evaluate scope alternatives, timelines, cost inputs, and operational feasibility.
• Improve delivery processes and knowledge transfer by documenting repeatable workflows, clarifying ownership, creating training materials, and ensuring critical program and account knowledge is transferable across the team.
• Lead and champion program management best practices, creating consistent ways of working across teams for planning, execution, risk management, communication, and delivery

What success looks like

• Client programs are delivered against agreed scope, timelines, budget, and client commitments, with deviations proactively managed and communicated.
• Clients have a clear, reliable view of milestones, deliverables, owners, and changes.
• Internal teams understand the scientific and commercial context of their work.
• Risks and dependency conflicts are identified and addressed early, with explicit options and decisions.
• Program plans reflect reliable data and actual operational capacity rather than only desired timelines.
• Data, methods, and client-facing materials are delivered in an organized, predictable way.
• Program knowledge is well-documented for clean account ownership transfers.
• Client delivery and internal R&D priorities are effectively balanced and coordinated.

Requirements and Expectations

• 5+ years of experience leading complex, cross-functional programs in biotech, pharma, life sciences, CRO/CDMO, healthcare technology, or a similarly technical client-delivery environment.
• Strong client-facing communication skills, including the ability to manage senior external stakeholders and communicate schedule changes, risks, and trade-offs clearly.
• Demonstrated ability to develop and maintain detailed project plans, milestones, dependencies, resourcing views, and operating cadences.
• Proven track record of driving complex programs through execution and delivery, managing scope, timelines, budgets, risks, and competing priorities.
• Comfort working with scientific teams and technical subject matter without needing to be the scientific owner.
• Experience coordinating and managing deliverables such as study plans, work plans, technical reports, presentations, data packages, and client communications.
• Strong organizational and program-management systems skills; experience with ClickUp or comparable project-management tools is preferred.
• Sound judgment under ambiguity and an ability to move work forward across competing priorities.
• Polished written and verbal communication skills for both technical and executive audiences.

Preferred Qualifications

• Prior experience working with biotech R&D, computational biology, or AI-enabled scientific programs.
• Experience scaling operational processes in a fast-growth startup or similarly dynamic environment.

Additional information

Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee's geographic location.

Pay and benefits

Pay Range $175,000—$223,000 USD