Flagship Pioneering
Direct Greenhouse career site

Senior Strategic Transactions Lead, APEX

Location
Cambridge, MA USA · On-site
Job type
Full-time
Level
Director
Listed
31 days ago

Skills & highlights for this role

  • M&A transaction execution
  • joint ventures and partnerships
  • deal structuring

Also useful

  • IPO process
  • licensing and collaboration deals
  • global fundraising

Position Summary

Flagship Pioneering is seeking a highly motivated Senior Strategic Transaction Leader to join our growing Transactions team. Flagship undertakes dozens of complex and value-oriented transactions at any given time, including complex joint ventures and partnerships, mergers and acquisition, initial public offerings, licensing and collaborations, global fundraising as well as and business and corporate development initiatives.

All the activities associated with transactions at Flagship are led by a cross-disciplinary group, referred to internally as the "APEX Group". APEX is an acronym for "Acquisitions, Partnership, Equity and eXecution."

This is an outstanding opportunity for an experienced strategic business leader with strong transaction experience who wants exposure to some of the most innovative companies and partnerships involved in ground-breaking transactions.This individual will partner closely with other business leaders in working on transactions, including members of Flagship's Executive Leadership Team, Business Development, Corporate Development, senior management of portfolio companies and other leadership teams to help execute a wide range of strategic transactions across the Flagship ecosystem.

Responsibilities

  • Own and drive, together with other members of the APEX Group, the execution of transactions across the Flagship ecosystem, including licensing, collaboration, financing, partnership, joint venture, M&A, and other strategic transactions as well as venture financings, equity investments, recapitalizations, and other capital accessing activities
  • Coordinate with other colleagues at Flagship and external advisors to facilitate great decision-making.
  • Drive the design and strategic structuring of complex transactions to achieve financial objectives.
  • Mentor, oversee and develop younger colleagues in the Apex group
  • Drive the negotiation of transaction terms and the completion of relevant processes.
  • Manage multiple transactions simultaneously in a fast-paced, entrepreneurial environment.
  • Stay ahead of industry trends, evolving regulations, and legal developments impacting pharmaceutical collaborations and biotech transactions.
  • Contribute to developing and implementing best practices, templates, and playbooks to streamline relevant transaction processes.
  • Proactively engage and direct external law firm partners and advisors to manage high-stakes negotiations and complex deal structures and legal cost associated with the same.
  • Counsel internal stakeholders on legal interpretations, risk management and compliance considerations.

Qualifications & Experience

  • J.D. from a top-tier law school, or equivalent graduate school degree in a relevant field
  • 10+ years of experience in complex life sciences transactions, including top-tier law firm experience or top-tier investment bank, consulting firm or investment firm; previous in-house pharma experience is preferred but not required.
  • Deep expertise in corporate transactions and financings, including pharmaceutical collaborations, licensing agreements, and other significant transactions.
  • Proven ability to lead negotiations on complex, high-value deals in the biotech or pharmaceutical industry.
  • Excellent executive presence, communication, leadership, and problem-solving skills, with the ability to advise senior executives and drive strategic decision-making.

What Makes You Successful

You are someone who

  • Thrives in ambiguity and enjoys solving complex business problems.
  • Is equally comfortable discussing financial models, business strategy, legal agreements, and transaction structures.
  • Can move seamlessly between detailed execution and strategic thinking.
  • Builds strong relationships across diverse teams.
  • Has exceptional judgment, curiosity, and attention to detail.
  • Enjoys working in a fast-moving, innovative environment where no two transactions are alike.

About Flagship Pioneering

Flagship Pioneering invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond.

What sets Flagship apart is our ability to unite life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs that generate exceptional value for people and the planet.

Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been named four times to Fast Company's annual list of the World's Most Innovative Companies.

Why Join Flagship?

At Flagship, you'll have the opportunity to work on groundbreaking transactions that help launch and scale pioneering science and technology companies. You'll gain exposure to company creation and building, venture financing, strategic partnerships, licensing, acquisitions, and innovative business models while working alongside leaders across science, investing, legal, finance, and business development.

This role offers exceptional breadth, responsibility, and learning for someone looking to build a long-term career at the intersection of innovation, transactions, and company building.

#LI-NM1

Read the original posting

From Flagship Pioneering's careers page, first listed on Rolev.ai on October 10, 2026. Rolev.ai is not the employer.

How Rolev.ai helps with this application

Rolev.ai is a job search and application tool for US job seekers. For this Senior Strategic Transactions Lead, APEX role at Flagship Pioneering, it shows how your resume fits, tailors your resume to the posting, and prepares the application for you to review.

  • See how you fit

    Openings from employer career sites are ranked against your whole resume—and searchable inside Claude, ChatGPT, and Cursor via Rolev.ai MCP.

  • Tailor without inventing

    Every change to your resume is checked against your original. New experience goes in only with your yes—zero fabricated claims.

  • Draft the full kit

    Tailored and Full Match resumes, role-specific cover letters, and answers to employer screening questions are prepared in seconds.

  • 1-Click Extension Autofill

    The Chrome extension fills the employer's Greenhouse, Workday, Lever, or Ashby form in 1 click. You review it and press Submit.

Common questions

Where is the Senior Strategic Transactions Lead, APEX job at Flagship Pioneering located?

This Senior Strategic Transactions Lead, APEX position at Flagship Pioneering is located in Cambridge, MA USA (On-site). Always check Flagship Pioneering's application page for specific state eligibility or relocation policies.

What qualifications are required for Senior Strategic Transactions Lead, APEX at Flagship Pioneering?

For the Senior Strategic Transactions Lead, APEX role, Flagship Pioneering highlights experience with M&A transaction execution, joint ventures and partnerships, deal structuring. Rolev.ai can score your existing resume against these requirements and show any skill gaps before you apply.

How do I apply for the Senior Strategic Transactions Lead, APEX position at Flagship Pioneering?

This listing links directly to Flagship Pioneering's Greenhouse application page. You can apply directly on Flagship Pioneering's site, or use Rolev.ai to check your resume fit, generate a zero-hallucination tailored resume and cover letter for this posting, and autofill the Greenhouse application form in 1 click with the Rolev.ai Chrome extension. You always review the form and press Submit yourself.